Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells

Artonin E is a prenylated flavonoid compound isolated from the stem bark of Artocarpus elasticus. This phytochemical has been previously reported to be drug-like with full compliance to Lipinski’s rule of five and good physicochemical properties when compared with 95% of orally available drugs. It h...

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Bibliographic Details

Main Authors:	Etti, I.C., Abdullah, R., Hashim, N.M., Abdul, A.B., Kadir, A., Yeap, S.K., Waziri, P., Malami, I., Lim, K.L., Etti, C.J.
Format:	Article
Published:	Dove Medical Press 2017
Subjects:	Q Science (General) R Medicine
Online Access:	http://eprints.um.edu.my/19187/ http://dx.doi.org/10.2147/DDDT.S124324
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