NMDA receptor antagonism with novel indolyl, 2-(1,1-Dimethyl-1,3-dihydro-benzo[e]indol-2-ylidene)-malonaldehyde, reduces seizures duration in a rat model of epilepsy
N-methyl-D-aspartate receptors (NMDAR) play a central role in epileptogensis and NMDAR antagonists have been shown to have antiepileptic effects in animals and humans. Despite significant progress in the development of antiepileptic therapies over the previous 3 decades, a need still exists for nove...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | en |
| Published: |
Nature Publishing Group
2017
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/19038/1/NMDA_receptor_antagonism_with_novel_indolyl.pdf http://eprints.um.edu.my/19038/ http://dx.doi.org/10.1038/srep45540 |
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