VP1 residues around the five-fold axis of enterovirus A71 mediate heparan sulfate interaction

Enterovirus A71 (EV-A71) is a neurotropic enterovirus that uses heparan sulfate as an attachment receptor. The molecular determinants of EV-A71-heparan sulfate interaction are unknown. With In silico heparin docking and mutagenesis of all possible lysine residues in VP1, we identified that K162, K24...

Full description

Bibliographic Details

Main Authors:	Tan, C.W., Sam, I.C., Lee, V.S., Wong, H.V., Chan, Y.F.
Format:	Article
Published:	Elsevier 2017
Subjects:	QD Chemistry R Medicine
Online Access:	http://eprints.um.edu.my/19012/ http://dx.doi.org/10.1016/j.virol.2016.11.009
Tags:	Add Tag No Tags, Be the first to tag this record!