Synthesis of selected pyrazine derivatives and their photopyhsical characteristics
2-Phenoxypyrazine, 2-o-methyphenoxypyrazine, 2-m-methylphenoxypyrazine, and 2-p-methylphenoxypyrazine were obtained when 2-chloropyrazine was treated with phenol, o-cresol, m-cresol and p-cresol respectively. Reactions of 2-choropyrazine-5-carboxylic acid methyl ester with phenol, 3-methylphenol and...
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| Language: | en |
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2018
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| Online Access: | http://eprints.um.edu.my/19002/1/Organic_and_iniorganic_chemstry.pdf http://eprints.um.edu.my/19002/ https://www.omicsonline.org/conference-proceedings/2150-3494-C4-026-003.pdf |
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| _version_ | 1831506447833235456 |
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| author | Abdullah, Z. Johari, H.N. Idris, A. |
| author_facet | Abdullah, Z. Johari, H.N. Idris, A. |
| author_sort | Abdullah, Z. |
| building | UM Library |
| collection | Institutional Repository |
| content_provider | Universiti Malaya |
| content_source | UM Research Repository |
| continent | Asia |
| country | Malaysia |
| description | 2-Phenoxypyrazine, 2-o-methyphenoxypyrazine, 2-m-methylphenoxypyrazine, and 2-p-methylphenoxypyrazine were obtained when 2-chloropyrazine was treated with phenol, o-cresol, m-cresol and p-cresol respectively. Reactions of 2-choropyrazine-5-carboxylic acid methyl ester with phenol, 3-methylphenol and 3-nitrophenol gave 5-phenoxypyrazine- 2-carboxylic acid, 5-m-tolyoxyprazine-2-carboxyclic acid methyl ester and 5-(-3-nitrophenoxy) pyrazine-2-carboxyliic acid methyl ester respectively. 2.5-Dimethyl-3-phenoxypyrazine was obtained when phenol was reacted with 3-chloro- 2,5-dimethylpyrazine. Naphthalenyloxy derivatives were obtained when 2- chloropyrazine reacted with 1 and 2- naphtol respectively. The structures of newly synthesized compounds were spectroscopically characterized. Fluorescence studies showed that compounds 2, 4 and 8 quenched in the presence of oxygen. Compounds 1 and 7 showed the highest fluorescence intensity in alkaline condition. Compound 1, 4 and 8 exhibit the highest emission wavelength in non-polar solvents and falls drastically in polar aprotic solvents. Highest fluorescence intensity was recorded with compounds which have electron donating substituents and has rigid structure. |
| format | Conference or Workshop Item |
| id | my.um.eprints-19002 |
| institution | Universiti Malaya |
| language | en |
| publishDate | 2018 |
| record_format | eprints |
| spelling | my.um.eprints-190022018-08-17T04:33:07Z http://eprints.um.edu.my/19002/ Synthesis of selected pyrazine derivatives and their photopyhsical characteristics Abdullah, Z. Johari, H.N. Idris, A. Q Science (General) QD Chemistry 2-Phenoxypyrazine, 2-o-methyphenoxypyrazine, 2-m-methylphenoxypyrazine, and 2-p-methylphenoxypyrazine were obtained when 2-chloropyrazine was treated with phenol, o-cresol, m-cresol and p-cresol respectively. Reactions of 2-choropyrazine-5-carboxylic acid methyl ester with phenol, 3-methylphenol and 3-nitrophenol gave 5-phenoxypyrazine- 2-carboxylic acid, 5-m-tolyoxyprazine-2-carboxyclic acid methyl ester and 5-(-3-nitrophenoxy) pyrazine-2-carboxyliic acid methyl ester respectively. 2.5-Dimethyl-3-phenoxypyrazine was obtained when phenol was reacted with 3-chloro- 2,5-dimethylpyrazine. Naphthalenyloxy derivatives were obtained when 2- chloropyrazine reacted with 1 and 2- naphtol respectively. The structures of newly synthesized compounds were spectroscopically characterized. Fluorescence studies showed that compounds 2, 4 and 8 quenched in the presence of oxygen. Compounds 1 and 7 showed the highest fluorescence intensity in alkaline condition. Compound 1, 4 and 8 exhibit the highest emission wavelength in non-polar solvents and falls drastically in polar aprotic solvents. Highest fluorescence intensity was recorded with compounds which have electron donating substituents and has rigid structure. 2018 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.um.edu.my/19002/1/Organic_and_iniorganic_chemstry.pdf Abdullah, Z. and Johari, H.N. and Idris, A. (2018) Synthesis of selected pyrazine derivatives and their photopyhsical characteristics. In: 5th International Conference on Organic and Inorganic Chemistry 2018, 12-13 July 2018, Paris, France. https://www.omicsonline.org/conference-proceedings/2150-3494-C4-026-003.pdf |
| spellingShingle | Q Science (General) QD Chemistry Abdullah, Z. Johari, H.N. Idris, A. Synthesis of selected pyrazine derivatives and their photopyhsical characteristics |
| title | Synthesis of selected pyrazine derivatives and their photopyhsical characteristics |
| title_full | Synthesis of selected pyrazine derivatives and their photopyhsical characteristics |
| title_fullStr | Synthesis of selected pyrazine derivatives and their photopyhsical characteristics |
| title_full_unstemmed | Synthesis of selected pyrazine derivatives and their photopyhsical characteristics |
| title_short | Synthesis of selected pyrazine derivatives and their photopyhsical characteristics |
| title_sort | synthesis of selected pyrazine derivatives and their photopyhsical characteristics |
| topic | Q Science (General) QD Chemistry |
| url | http://eprints.um.edu.my/19002/1/Organic_and_iniorganic_chemstry.pdf http://eprints.um.edu.my/19002/ https://www.omicsonline.org/conference-proceedings/2150-3494-C4-026-003.pdf |
| url_provider | http://eprints.um.edu.my/ |