Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice
A six-week-old male infant was admitted for investigation of cholestasis and pale stools. He became lethargic and apnoeic with prolonged seizures after a percutaneous liver biopsy. Subsequent investigations showed conjugated hyperbilirubinaemia, elevated liver enzymes, and hypoglycaemia. The radinuc...
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| Language: | en |
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Malaysian Medical Association
2003
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| Online Access: | http://eprints.um.edu.my/10921/1/Addisonian-like_crisis_in_congenital_hypopituitarism.pdf http://eprints.um.edu.my/10921/ http://www.e-mjm.org/2003/v58n2/Congenital_Hypopituitarism.pdf |
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| author | Lee, Way Seah Lum, L.C. Harun, F. |
| author_facet | Lee, Way Seah Lum, L.C. Harun, F. |
| author_sort | Lee, Way Seah |
| building | UM Library |
| collection | Institutional Repository |
| content_provider | Universiti Malaya |
| content_source | UM Research Repository |
| continent | Asia |
| country | Malaysia |
| description | A six-week-old male infant was admitted for investigation of cholestasis and pale stools. He became lethargic and apnoeic with prolonged seizures after a percutaneous liver biopsy. Subsequent investigations showed conjugated hyperbilirubinaemia, elevated liver enzymes, and hypoglycaemia. The radinuclide hepatobiliary scintigraphy was non-excretory. After an operative cholangiogram, the infant developed Addisonian-like crisis with bradycardia, hypotension, respiratory distress, metabolic acidosis, hypoglycaemia, hyponatraemia, and hyperkalaemia. Blood investigations confirmed congenital hypopituitarism. Hormone replacement therapy with L-thyroxine and cortisone acetate resulted in dissolution of jaundice and the reduction of the liver size. |
| format | Article |
| id | my.um.eprints-10921 |
| institution | Universiti Malaya |
| language | en |
| publishDate | 2003 |
| publisher | Malaysian Medical Association |
| record_format | eprints |
| spelling | my.um.eprints-109212019-03-01T06:05:14Z http://eprints.um.edu.my/10921/ Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice Lee, Way Seah Lum, L.C. Harun, F. R Medicine RJ Pediatrics A six-week-old male infant was admitted for investigation of cholestasis and pale stools. He became lethargic and apnoeic with prolonged seizures after a percutaneous liver biopsy. Subsequent investigations showed conjugated hyperbilirubinaemia, elevated liver enzymes, and hypoglycaemia. The radinuclide hepatobiliary scintigraphy was non-excretory. After an operative cholangiogram, the infant developed Addisonian-like crisis with bradycardia, hypotension, respiratory distress, metabolic acidosis, hypoglycaemia, hyponatraemia, and hyperkalaemia. Blood investigations confirmed congenital hypopituitarism. Hormone replacement therapy with L-thyroxine and cortisone acetate resulted in dissolution of jaundice and the reduction of the liver size. Malaysian Medical Association 2003 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10921/1/Addisonian-like_crisis_in_congenital_hypopituitarism.pdf Lee, Way Seah and Lum, L.C. and Harun, F. (2003) Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice. Medical Journal of Malaysia, 58 (2). pp. 279-281. ISSN 0300-5283, http://www.e-mjm.org/2003/v58n2/Congenital_Hypopituitarism.pdf |
| spellingShingle | R Medicine RJ Pediatrics Lee, Way Seah Lum, L.C. Harun, F. Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice |
| title | Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice |
| title_full | Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice |
| title_fullStr | Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice |
| title_full_unstemmed | Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice |
| title_short | Addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice |
| title_sort | addisonian-like crisis in congenital hypopituitarism and cholestatic jaundice |
| topic | R Medicine RJ Pediatrics |
| url | http://eprints.um.edu.my/10921/1/Addisonian-like_crisis_in_congenital_hypopituitarism.pdf http://eprints.um.edu.my/10921/ http://www.e-mjm.org/2003/v58n2/Congenital_Hypopituitarism.pdf |
| url_provider | http://eprints.um.edu.my/ |