Drivers and passengers on the road to lung cancer

Lung cancer, the most common cancer and the leading cause of cancer death worldwide, arises as a result of somatically acquired changes in the DNA of the cancer cells. Genetic alterations called "driver" mutations responsible for cancer cell development, growth and survival coexist alongs...

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Main Author: Liam , Chong Kin
Format: Book
Published: University Of Malaya 2015
Subjects:
Online Access:http://commonrepo.um.edu.my/13294/1/Inaugural%20Lecture%20Professor%20Dr%20liam%20Chong%20Kin.pdf
http://commonrepo.um.edu.my/13294/
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author Liam , Chong Kin
author_facet Liam , Chong Kin
author_sort Liam , Chong Kin
building UM Library
collection Institutional Repository
content_provider Universiti Malaya
content_source UM Common Repository
continent Asia
country Malaysia
description Lung cancer, the most common cancer and the leading cause of cancer death worldwide, arises as a result of somatically acquired changes in the DNA of the cancer cells. Genetic alterations called "driver" mutations responsible for cancer cell development, growth and survival coexist alongside thousands of "passenger" mutations which do not contribute to carcinogenesis but have hitchhiked along for the ride. The last decade has witnessed an enormous advancement in the treatment for advanced non-small-cell lung cancer with the discovery of several driver oncogenes leading to the development of personalised oncogene-directed targeted therapies with better response and improved survival.
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spelling my.um.common-132942023-01-18T08:16:49Z Drivers and passengers on the road to lung cancer Liam , Chong Kin R Medicine (General) Lung cancer, the most common cancer and the leading cause of cancer death worldwide, arises as a result of somatically acquired changes in the DNA of the cancer cells. Genetic alterations called "driver" mutations responsible for cancer cell development, growth and survival coexist alongside thousands of "passenger" mutations which do not contribute to carcinogenesis but have hitchhiked along for the ride. The last decade has witnessed an enormous advancement in the treatment for advanced non-small-cell lung cancer with the discovery of several driver oncogenes leading to the development of personalised oncogene-directed targeted therapies with better response and improved survival. University Of Malaya 2015 Book NonPeerReviewed application/pdf http://commonrepo.um.edu.my/13294/1/Inaugural%20Lecture%20Professor%20Dr%20liam%20Chong%20Kin.pdf Liam , Chong Kin (2015) Drivers and passengers on the road to lung cancer. University Of Malaya. (Unpublished) http://commonrepo.um.edu.my/13294/
spellingShingle R Medicine (General)
Liam , Chong Kin
Drivers and passengers on the road to lung cancer
title Drivers and passengers on the road to lung cancer
title_full Drivers and passengers on the road to lung cancer
title_fullStr Drivers and passengers on the road to lung cancer
title_full_unstemmed Drivers and passengers on the road to lung cancer
title_short Drivers and passengers on the road to lung cancer
title_sort drivers and passengers on the road to lung cancer
topic R Medicine (General)
url http://commonrepo.um.edu.my/13294/1/Inaugural%20Lecture%20Professor%20Dr%20liam%20Chong%20Kin.pdf
http://commonrepo.um.edu.my/13294/
url_provider http://commonrepo.um.edu.my/