Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar
Pyogenic granuloma-like Kaposi sarcoma (PGLKS) is an uncommon variant of Kaposi sarcoma (KS), which mimics benign pyogenic granuloma both clinically and histologically. We report a case of PGLKS of the toe occurring in a HIV-positive individual. It presented as a 2cm skin swelling of 2 weeks’ durati...
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Universiti Teknologi MARA Cawangan Selangor
2020
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| Online Access: | https://ir.uitm.edu.my/id/eprint/44193/1/44193.pdf https://ir.uitm.edu.my/id/eprint/44193/ https://jchs-medicine.uitm.edu.my/index.php |
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| _version_ | 1833067476146978816 |
|---|---|
| author | Abdul Aziz, Mardiana Abdul Aziz Omar, Effat Omar |
| author_facet | Abdul Aziz, Mardiana Abdul Aziz Omar, Effat Omar |
| author_sort | Abdul Aziz, Mardiana Abdul Aziz |
| building | Tun Abdul Razak Library |
| collection | Institutional Repository |
| content_provider | Universiti Teknologi Mara |
| content_source | UiTM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Pyogenic granuloma-like Kaposi sarcoma (PGLKS) is an uncommon variant of Kaposi sarcoma (KS), which mimics benign pyogenic granuloma both clinically and histologically. We report a case of PGLKS of the toe occurring in a HIV-positive individual. It presented as a 2cm skin swelling of 2 weeks’ duration which was clinically felt to be a pyogenic granuloma. Histopathological examination revealed a polypoid atypical vascular lesion with overlying peripheral epidermal collarette. Spindle cell proliferation typically seen in KS was also identified, which was positive for human herpesvirus 8 (HHV8) by immunohistochemistry, confirming the diagnosis of PGLKS. Upon review of the literature, our case is the 29th case of PGLKS reported to date, and only the sixth in Asian population. Particular attention to histomorphology, and demonstration of HHV8 in lesional tissue will aid accurate diagnosis of this rare entity. |
| format | Article |
| id | my.uitm.ir-44193 |
| institution | Universiti Teknologi Mara |
| language | en |
| publishDate | 2020 |
| publisher | Universiti Teknologi MARA Cawangan Selangor |
| record_format | eprints |
| spelling | my.uitm.ir-441932021-03-24T15:07:01Z https://ir.uitm.edu.my/id/eprint/44193/ Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar jchs Abdul Aziz, Mardiana Abdul Aziz Omar, Effat Omar RB Pathology Neoplasms. Tumors. Oncology Pyogenic granuloma-like Kaposi sarcoma (PGLKS) is an uncommon variant of Kaposi sarcoma (KS), which mimics benign pyogenic granuloma both clinically and histologically. We report a case of PGLKS of the toe occurring in a HIV-positive individual. It presented as a 2cm skin swelling of 2 weeks’ duration which was clinically felt to be a pyogenic granuloma. Histopathological examination revealed a polypoid atypical vascular lesion with overlying peripheral epidermal collarette. Spindle cell proliferation typically seen in KS was also identified, which was positive for human herpesvirus 8 (HHV8) by immunohistochemistry, confirming the diagnosis of PGLKS. Upon review of the literature, our case is the 29th case of PGLKS reported to date, and only the sixth in Asian population. Particular attention to histomorphology, and demonstration of HHV8 in lesional tissue will aid accurate diagnosis of this rare entity. Universiti Teknologi MARA Cawangan Selangor 2020-11-01 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/44193/1/44193.pdf Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar. (2020) Journal of Clinical and Health Sciences <https://ir.uitm.edu.my/view/publication/Journal_of_Clinical_and_Health_Sciences/>, 5 (2). pp. 66-74. ISSN 0127-984X https://jchs-medicine.uitm.edu.my/index.php |
| spellingShingle | RB Pathology Neoplasms. Tumors. Oncology Abdul Aziz, Mardiana Abdul Aziz Omar, Effat Omar Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar |
| title | Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar |
| title_full | Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar |
| title_fullStr | Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar |
| title_full_unstemmed | Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar |
| title_short | Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar |
| title_sort | pyogenic granuloma-like kaposi sarcoma: case report and review of literature / mardiana abdul aziz and effat omar |
| topic | RB Pathology Neoplasms. Tumors. Oncology |
| url | https://ir.uitm.edu.my/id/eprint/44193/1/44193.pdf https://ir.uitm.edu.my/id/eprint/44193/ https://jchs-medicine.uitm.edu.my/index.php |
| url_provider | http://ir.uitm.edu.my/ |