Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD)
Did you know that over 1 in 4 people worldwide may have fatty liver disease and most don’t even know it? Metabolic dysfunction-associated fatty liver disease (MAFLD) is a chronic liver condition characterised by the accumulation of fat in the liver, accompanied by metabolic abnormalities such as obe...
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| Language: | en |
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Faculty of Pharmacy
2025
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| Online Access: | https://ir.uitm.edu.my/id/eprint/120708/1/120708.pdf https://ir.uitm.edu.my/id/eprint/120708/ |
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| _version_ | 1842128962113765376 |
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| author | Mohamad, Mashani |
| author_facet | Mohamad, Mashani |
| author_sort | Mohamad, Mashani |
| building | Tun Abdul Razak Library |
| collection | Institutional Repository |
| content_provider | Universiti Teknologi Mara |
| content_source | UiTM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Did you know that over 1 in 4 people worldwide may have fatty liver disease and most don’t even know it? Metabolic dysfunction-associated fatty liver disease (MAFLD) is a chronic liver condition characterised by the accumulation of fat in the liver, accompanied by metabolic abnormalities such as obesity, insulin resistance (IR), type 2 diabetes, or metabolic dysregulation. MAFLD pathologies range from simple steatosis to a more severe inflammatory form known as metabolic dysfunction-associated steatohepatitis (MASH). MASH is marked by hepatocyte injury, fibrosis, and an increased risk of cirrhosis and hepatocellular carcinoma . Because MAFLD often presents with no symptoms in its early stages, many individuals remain unaware of the disease until significant liver damage has already occurred. |
| format | Article |
| id | my.uitm.ir-120708 |
| institution | Universiti Teknologi Mara |
| language | en |
| publishDate | 2025 |
| publisher | Faculty of Pharmacy |
| record_format | eprints |
| spelling | my.uitm.ir-1207082025-08-26T07:54:09Z https://ir.uitm.edu.my/id/eprint/120708/ Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) Mohamad, Mashani Metabolic diseases Diseases of the digestive system. Gastroenterology Did you know that over 1 in 4 people worldwide may have fatty liver disease and most don’t even know it? Metabolic dysfunction-associated fatty liver disease (MAFLD) is a chronic liver condition characterised by the accumulation of fat in the liver, accompanied by metabolic abnormalities such as obesity, insulin resistance (IR), type 2 diabetes, or metabolic dysregulation. MAFLD pathologies range from simple steatosis to a more severe inflammatory form known as metabolic dysfunction-associated steatohepatitis (MASH). MASH is marked by hepatocyte injury, fibrosis, and an increased risk of cirrhosis and hepatocellular carcinoma . Because MAFLD often presents with no symptoms in its early stages, many individuals remain unaware of the disease until significant liver damage has already occurred. Faculty of Pharmacy 2025-06 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/120708/1/120708.pdf Mohamad, Mashani (2025) Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD). (2025) Prescription <https://ir.uitm.edu.my/view/publication/Prescription.html> (6): 2. |
| spellingShingle | Metabolic diseases Diseases of the digestive system. Gastroenterology Mohamad, Mashani Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) |
| title | Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) |
| title_full | Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) |
| title_fullStr | Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) |
| title_full_unstemmed | Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) |
| title_short | Unravelling the immunometabolic role of liver sinusoidal endothelial cells (LSECs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD) |
| title_sort | unravelling the immunometabolic role of liver sinusoidal endothelial cells (lsecs) in the pathogenesis of metabolic dysfunction-associated fatty liver disease (mafld) |
| topic | Metabolic diseases Diseases of the digestive system. Gastroenterology |
| url | https://ir.uitm.edu.my/id/eprint/120708/1/120708.pdf https://ir.uitm.edu.my/id/eprint/120708/ |
| url_provider | http://ir.uitm.edu.my/ |