Formulation and evaluation of phyllanthus niruril chewable tablet / Nuru Alwani Abdul Manan

The aim of this study was to formulate Phyllanthus niruri chewable tablet 250 mg and to conduct customer acceptance study towards the newly formulated product. The tablet was prepared by using wet granulation process and physical characterization tests were carried out by collecting a sample of tabl...

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Bibliographic Details
Main Author: Abdul Manan, Nuru Alwani
Format: Thesis
Language:en
Published: 2009
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/106934/1/106934.PDF
https://ir.uitm.edu.my/id/eprint/106934/
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Summary:The aim of this study was to formulate Phyllanthus niruri chewable tablet 250 mg and to conduct customer acceptance study towards the newly formulated product. The tablet was prepared by using wet granulation process and physical characterization tests were carried out by collecting a sample of tablets from the batch and determining their uniformity of weight, hardness, thickness, diameter and friability. The customer acceptance study was done by distributing questionnaires to 30 Universiti Teknologi MARA students. The results showed that the formulated Phyllanthus niruri chewable tablet was hygroscopic and easily oxidized. The shape, colour uniformity and texture of the tablets are significantly (p < 0.1) influencing the customers' satisfaction towards physical appearance of the product. In terms of taste, the customers' satisfaction are significantly (p < 0.1) influenced by sweetness, sour and cola flavor of the product. Further formulation study should be conducted in determining the best formulation of Phyllanthus niruri chewable tablet with emphasizing on how to minimize the degradation process of the tablet particularly through oxidation.