Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay
The crystal and molecular structures of (Ph3P)2M[S2CN(Me)CH2CH2OH], M=Cu, isolated as a 1:1 dichloromethane solvate (1·CH2Cl2), and M=Ag (4) show the central metal atom to be coordinated by a symmetrically (1·CH2Cl2) and asymmetrically chelating (4) dithiocarbamate ligand. The distorted tetrahedral...
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De Gruyter
2016
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| Online Access: | http://eprints.sunway.edu.my/656/1/Z.%20Kristallogr.%202016%20231%20341.pdf http://eprints.sunway.edu.my/656/ http://dx.doi.org/10.1515/zkri-2016-0003 |
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| author | Nazzatush Shimar Jamaludin, Siti Nadiah Abdul Halim, Khoo, Chai-Hoon Chen, Bao-Jing See, Tian-Hong Sim, Jiun-Horng Cheah, Yoke-Kqueen Seng, Hoi-Ling * Tiekink, Edward R. T. * |
| author_facet | Nazzatush Shimar Jamaludin, Siti Nadiah Abdul Halim, Khoo, Chai-Hoon Chen, Bao-Jing See, Tian-Hong Sim, Jiun-Horng Cheah, Yoke-Kqueen Seng, Hoi-Ling * Tiekink, Edward R. T. * |
| author_sort | Nazzatush Shimar Jamaludin, |
| building | Sunway Campus Library |
| collection | Institutional Repository |
| content_provider | Sunway University |
| content_source | Sunway Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | The crystal and molecular structures of (Ph3P)2M[S2CN(Me)CH2CH2OH], M=Cu, isolated as a 1:1 dichloromethane solvate (1·CH2Cl2), and M=Ag (4) show the central metal atom to be coordinated by a symmetrically (1·CH2Cl2) and asymmetrically chelating (4) dithiocarbamate ligand. The distorted tetrahedral geometries are completed by two PPh3 ligands. The presence of hydroxyl-O–H···S(dithiocarbamate) hydrogen bonds leads to centrosymmetric dimeric aggregates in each crystal structure. In the molecular packing of 1·CH2Cl2, channels comprising 1 are formed via aryl-C–H···O interactions with the solvent molecules associated with the walls of the channels via methylene-C–H···S, π(aryl) interactions. For 4, the dimeric aggregates are connected via a network of aryl-C–H···π(aryl) interactions. Preliminary screening for anti-microbial activity was conducted. The compounds were only potent against Gram-positive bacteria. Some further selectivity in activity was noted. Most notably, all compounds were active against methicillin resistant Staphylococcus aureus. |
| format | Article |
| id | my.sunway.eprints.656 |
| institution | Sunway University |
| language | en |
| publishDate | 2016 |
| publisher | De Gruyter |
| record_format | eprints |
| spelling | my.sunway.eprints.6562020-10-07T09:56:30Z http://eprints.sunway.edu.my/656/ Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay Nazzatush Shimar Jamaludin, Siti Nadiah Abdul Halim, Khoo, Chai-Hoon Chen, Bao-Jing See, Tian-Hong Sim, Jiun-Horng Cheah, Yoke-Kqueen Seng, Hoi-Ling * Tiekink, Edward R. T. * QD Chemistry The crystal and molecular structures of (Ph3P)2M[S2CN(Me)CH2CH2OH], M=Cu, isolated as a 1:1 dichloromethane solvate (1·CH2Cl2), and M=Ag (4) show the central metal atom to be coordinated by a symmetrically (1·CH2Cl2) and asymmetrically chelating (4) dithiocarbamate ligand. The distorted tetrahedral geometries are completed by two PPh3 ligands. The presence of hydroxyl-O–H···S(dithiocarbamate) hydrogen bonds leads to centrosymmetric dimeric aggregates in each crystal structure. In the molecular packing of 1·CH2Cl2, channels comprising 1 are formed via aryl-C–H···O interactions with the solvent molecules associated with the walls of the channels via methylene-C–H···S, π(aryl) interactions. For 4, the dimeric aggregates are connected via a network of aryl-C–H···π(aryl) interactions. Preliminary screening for anti-microbial activity was conducted. The compounds were only potent against Gram-positive bacteria. Some further selectivity in activity was noted. Most notably, all compounds were active against methicillin resistant Staphylococcus aureus. De Gruyter 2016 Article PeerReviewed text en http://eprints.sunway.edu.my/656/1/Z.%20Kristallogr.%202016%20231%20341.pdf Nazzatush Shimar Jamaludin, and Siti Nadiah Abdul Halim, and Khoo, Chai-Hoon and Chen, Bao-Jing and See, Tian-Hong and Sim, Jiun-Horng and Cheah, Yoke-Kqueen and Seng, Hoi-Ling * and Tiekink, Edward R. T. * (2016) Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay. Zeitschrift für Kristallographie - Crystalline Materials, 231 (6). pp. 341-349. ISSN 2194-4946 http://dx.doi.org/10.1515/zkri-2016-0003 doi:10.1515/zkri-2016-0003 |
| spellingShingle | QD Chemistry Nazzatush Shimar Jamaludin, Siti Nadiah Abdul Halim, Khoo, Chai-Hoon Chen, Bao-Jing See, Tian-Hong Sim, Jiun-Horng Cheah, Yoke-Kqueen Seng, Hoi-Ling * Tiekink, Edward R. T. * Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay |
| title | Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay |
| title_full | Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay |
| title_fullStr | Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay |
| title_full_unstemmed | Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay |
| title_short | Bis(phosphane)copper(I) and silver(I) dithiocarbamates: crystallography and anti-microbial assay |
| title_sort | bis(phosphane)copper(i) and silver(i) dithiocarbamates: crystallography and anti-microbial assay |
| topic | QD Chemistry |
| url | http://eprints.sunway.edu.my/656/1/Z.%20Kristallogr.%202016%20231%20341.pdf http://eprints.sunway.edu.my/656/ http://dx.doi.org/10.1515/zkri-2016-0003 |
| url_provider | http://eprints.sunway.edu.my/ |