Genetic variations in methotrexate metabolic pathway genes influence methotrexate responses in rheumatoid arthritis patients in Malaysia

Methotrexate (MTX) is the most widely used disease-modifying anti-rheumatic drug (DMARD) for rheumatoid arthritis (RA). Many studies have attempted to understand the genetic risk factors that affect the therapeutic outcomes in RA patients treated with MTX. Unlike other studies that focus on the popu...

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Main Authors:	Sha, Hong Xi, Veerapen, Kumar, Chow, Sook Khuan *, Gun, Suk Chyn, Lau, Ing Soo, Lim, Renee Lay Hong, Zaliha, Zulkifli, Yow, Yoon Yen *, Peh, Suat Cheng *, Hwang, Jung Shan *
Format:	Article
Language:	en
Published:	Nature Publishing Group 2022
Subjects:	RC Internal medicine RM Therapeutics. Pharmacology
Online Access:	http://eprints.sunway.edu.my/3060/1/Yow%20Yoon%20Yen_Genetic%20variations%20in%20methotrexate%20metabolic%20pathway%20genes%20influence.pdf http://eprints.sunway.edu.my/3060/ https://doi.org/10.1038/s41598-022-15991-0
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