Editorial: Targeting signalling pathways in inflammatory diseases
Chronic inflammation, characterized by a persistent elevation of circulating pro-inflammatory cytokines, is associated with the pathogenesis of many non-communicable diseases that cause a worldwide health burden and a reduction in quality of life (1). The identification of possible therapeutic targe...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
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Frontiers Media
2023
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| Subjects: | |
| Online Access: | http://eprints.sunway.edu.my/2759/ https://doi.org/10.3389/fimmu.2023.1241440 |
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| Summary: | Chronic inflammation, characterized by a persistent elevation of circulating pro-inflammatory cytokines, is associated with the pathogenesis of many non-communicable diseases that cause a worldwide health burden and a reduction in quality of life (1). The identification of possible therapeutic targets implicated in the regulation of inflammation offers the opportunity to limit the dangers associated with an imbalance in the inflammatory response (2). Adaptor proteins represent key signaling molecules that regulate the host’s innate immune response to infections, acting as links between receptors and other molecules in several signaling cascades (3, 4). The evident importance of these proteins in the pathophysiology of different chronic inflammatory illnesses makes them attractive therapeutic targets (4). |
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