Optimization of a Luteolin-Loaded TPGS/Poloxamer 407 Nanomicelle: The Effects of Copolymers, Hydration Temperature and Duration, and Freezing Temperature on Encapsulation Efficiency, Particle Size, and Solubility

Background: Luteolin is a flavonoid compound that has been widely studied for its various anti-cancer properties and sensitization to multidrug-resistant cells. However, the limited solubility and bioavailability of Lut hindered its potential clinical use. Theoretically, the combination of this comp...

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Main Authors:	Muhammad Redza, Fahmi Mod Razif, Chan, Siok Yee, Riyanto, Teguh Widodo, Chew, Yik-Ling, Masriana, Hassan, Shairyzah, Ahmad Hisham, Shamima, Abdul Rahman, Long, Chiau Ming *, Tan, Ching Siang, Lee, Siew-Keah, Liew, Kai Bin
Format:	Article
Language:	en
Published:	MDPI 2023
Subjects:	QC Physics QD Chemistry RC Internal medicine RS Pharmacy and materia medica
Online Access:	http://eprints.sunway.edu.my/2713/1/Long%20Chiau%20Ming_Optimization%20of%20a%20Luteolin-loaded%20TPGS.pdf http://eprints.sunway.edu.my/2713/ https://doi.org/10.3390/cancers15143741
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