HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation

The Herpes Simplex Virus (HSV-1) immediate-early protein ICP22 interacts with cellular proteins to inhibit host cell gene expression and promote viral gene expression. ICP22 inhibits phosphorylation of Ser2 of the RNA polymerase II (pol II) carboxyl-terminal domain (CTD) and productive elongation of...

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Bibliographic Details

Main Authors:	Isa, Nur Firdaus, Bensaude, Olivier, Aziz, Nadiah C., Murphy, Shona
Format:	Article
Language:	en en
Published:	MDPI 2021
Subjects:	QR355 Virology RB Pathology
Online Access:	http://irep.iium.edu.my/92445/2/htm http://irep.iium.edu.my/92445/3/92445_HSV-1%20ICP22%20Is%20a%20Selective%20Viral%20Repressor.pdf http://irep.iium.edu.my/92445/ https://www.mdpi.com/2076-393X/9/10/1054 https://doi.org/10.3390/vaccines9101054
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