Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults

Hypertension and prehypertension are reversible risk factors for coronary artery disease (CAD). However, CAD risk is usually inadequately assessed in young adults and underestimated. This study aimed to investigate metabolic syndromecriteria including high-sensitive C-reactive protein...

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Main Authors: Mohamed Bakrim, Norbaiyah, Abdullah, Aszrin, Mohd. Shah, Aida Nur Sharini, A.Talib, Norlelawati, Wan Omar, Wan Fatein Nabeila, Mohd Shah, Azarisman Shah
Format: Article
Language:en
Published: Kulliyyah of Allied Health Sciences, International Islamic University Malaysia. 2021
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Online Access:http://irep.iium.edu.my/90821/7/90821%20METABOLIC%20SYNDROME%20AND%20HIGHSENSITIVE.pdf
http://irep.iium.edu.my/90821/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/575/541
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author Mohamed Bakrim, Norbaiyah
Abdullah, Aszrin
Mohd. Shah, Aida Nur Sharini
A.Talib, Norlelawati
Wan Omar, Wan Fatein Nabeila
Mohd Shah, Azarisman Shah
author_facet Mohamed Bakrim, Norbaiyah
Abdullah, Aszrin
Mohd. Shah, Aida Nur Sharini
A.Talib, Norlelawati
Wan Omar, Wan Fatein Nabeila
Mohd Shah, Azarisman Shah
author_sort Mohamed Bakrim, Norbaiyah
building IIUM Library
collection Institutional Repository
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
continent Asia
country Malaysia
description Hypertension and prehypertension are reversible risk factors for coronary artery disease (CAD). However, CAD risk is usually inadequately assessed in young adults and underestimated. This study aimed to investigate metabolic syndromecriteria including high-sensitive C-reactive protein (hs-CRP) in young hypertensive and prehypertensive adults. This was a cross-sectional study involving 120 male young adults aged < 45 years old; 40 subjects in control, prehypertensive and hypertensive group respectively. CAD risk factors; body mass index (BMI), waist circumference, lipid profiles, fasting blood glucose and hs-CRP levels were assessed in all subjects. Obesity and hypercholesterolemia were most prevalent in hypertensive, followed by prehypertensive and control group. Mean waist circumference was significantly higher in hypertension than the control (98.3±13.1 vs. 87.0±8.4 cm, p=0.018). Median hs-CRP was significantly higher in hypertension and prehypertension than the control (2.7 vs. 2.2±3.8 vs. 1.1±1.7 p<0.001). The high prevalence of metabolic syndrome and elevation of hs-CRP in young adults with hypertension and prehypertension indicate the increase risk of CAD among these cohorts. Hence, apart from management of high blood pressure, holistic risk modifications strategies such as weight loss, low cholesterol diet and physical exercise are essential to prevent premature CAD
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spelling my.iium.irep-908212021-07-30T06:33:13Z http://irep.iium.edu.my/90821/ Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults Mohamed Bakrim, Norbaiyah Abdullah, Aszrin Mohd. Shah, Aida Nur Sharini A.Talib, Norlelawati Wan Omar, Wan Fatein Nabeila Mohd Shah, Azarisman Shah R Medicine (General) RC Internal medicine Hypertension and prehypertension are reversible risk factors for coronary artery disease (CAD). However, CAD risk is usually inadequately assessed in young adults and underestimated. This study aimed to investigate metabolic syndromecriteria including high-sensitive C-reactive protein (hs-CRP) in young hypertensive and prehypertensive adults. This was a cross-sectional study involving 120 male young adults aged < 45 years old; 40 subjects in control, prehypertensive and hypertensive group respectively. CAD risk factors; body mass index (BMI), waist circumference, lipid profiles, fasting blood glucose and hs-CRP levels were assessed in all subjects. Obesity and hypercholesterolemia were most prevalent in hypertensive, followed by prehypertensive and control group. Mean waist circumference was significantly higher in hypertension than the control (98.3±13.1 vs. 87.0±8.4 cm, p=0.018). Median hs-CRP was significantly higher in hypertension and prehypertension than the control (2.7 vs. 2.2±3.8 vs. 1.1±1.7 p<0.001). The high prevalence of metabolic syndrome and elevation of hs-CRP in young adults with hypertension and prehypertension indicate the increase risk of CAD among these cohorts. Hence, apart from management of high blood pressure, holistic risk modifications strategies such as weight loss, low cholesterol diet and physical exercise are essential to prevent premature CAD Kulliyyah of Allied Health Sciences, International Islamic University Malaysia. 2021-04-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/90821/7/90821%20METABOLIC%20SYNDROME%20AND%20HIGHSENSITIVE.pdf Mohamed Bakrim, Norbaiyah and Abdullah, Aszrin and Mohd. Shah, Aida Nur Sharini and A.Talib, Norlelawati and Wan Omar, Wan Fatein Nabeila and Mohd Shah, Azarisman Shah (2021) Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults. International Journal of Allied Health Sciences (IJAHS), 5 (1 Special Issue). p. 2138. ISSN 2600-8491 https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/575/541
spellingShingle R Medicine (General)
RC Internal medicine
Mohamed Bakrim, Norbaiyah
Abdullah, Aszrin
Mohd. Shah, Aida Nur Sharini
A.Talib, Norlelawati
Wan Omar, Wan Fatein Nabeila
Mohd Shah, Azarisman Shah
Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults
title Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults
title_full Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults
title_fullStr Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults
title_full_unstemmed Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults
title_short Metabolic syndrome and high sensitive C-reactive protein In young hypertensive and prehypertensive adults
title_sort metabolic syndrome and high sensitive c-reactive protein in young hypertensive and prehypertensive adults
topic R Medicine (General)
RC Internal medicine
url http://irep.iium.edu.my/90821/7/90821%20METABOLIC%20SYNDROME%20AND%20HIGHSENSITIVE.pdf
http://irep.iium.edu.my/90821/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/575/541
url_provider http://irep.iium.edu.my/