Type-2 diabetes mellitus individuals carry different periodontal bacteria
Objective: To identify etiologic microbiota associated periodontal diseases among diabetes patients and the factors related to the most commonly identified bacteria species. Material and Methods: Periodontal plaque samples from 11 diabetic participants and 13 non-diabetic controls were collected t...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | en en en |
| Published: |
SciELO Analytics
2021
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/89742/1/89742_Type-2%20diabetes%20mellitus%20individuals.pdf http://irep.iium.edu.my/89742/2/89742_Type-2%20diabetes%20mellitus%20individuals_WoS.pdf http://irep.iium.edu.my/89742/3/89742_Type-2%20diabetes%20mellitus%20individuals_SCOPUS.pdf http://irep.iium.edu.my/89742/ https://doi.org/10.1590/pboci.2021.049 |
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| Summary: | Objective: To identify etiologic microbiota associated periodontal diseases among diabetes patients and the
factors related to the most commonly identified bacteria species. Material and Methods: Periodontal
plaque samples from 11 diabetic participants and 13 non-diabetic controls were collected to assess their
aerobic and anaerobic bacterial growth. Different distinct colonies were identified by microscopic and
16srDNA sequencing. Pearson's chi-square tests were conducted to examine any association between
categorical variables. Results: The diabetic subjects revealed a more intense plaque formation with a mean
plaque index of 2.4 compared to 1.8 in non-diabetics. A total of 86 bacteria were isolated from 24 plaque
samples, 44 were aerobic, and 42 were anaerobic. Only aerobic isolates, 22 from diabetic patients and 22
from non-diabetic patients, were evaluated in these analyses. Bacillus spp. (B. cereus mainly) and Klebsiella spp.
(K. pneumoniae, K. aerogenes, K. oxytoca) were detected markedly higher in non-diabetic individuals than in
diabetic subjects (p=0.026 and p=0.021, respectively). Some bacteria were only identified in the dental
plaque of diabetic individuals, namely, Bacillus mojavensis, Enterobacter cloacae, Proteus mirabilis, Staphylococcus
epidermidis, Staphylococcus hominis, Staphylococcus pasteuri, Streptococcus mutans, and Streptococcus pasteurianus. The presence of acid reflux and jaundice were significantly associated with the most common bacterial isolate, namely Bacillus spp., with the p-values of 0.007 and 0.001, respectively. Conclusion: Type-2 diabetes mellitus is associated with a higher amount of dental plaques. Periodontal plaque samples from diabetic and non-diabetic subjects possess differential microbial communities. Diabetic plaques contain more versatile microbes predominated by gram-positive streptococci and staphylococci. |
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