Synthesis, In silico molecular docking modeling and pharmacophore mapping of (E)-3-(4-hydroxy-2,6-dimethoxyphenyl)-1-phenylprop-2-en-1- one as potential new inhibitor of microsomal prostaglandin E synthase-1

The discovery of potent anti-inflammatory agents through inhibition of prostaglandin E2 (PGE2) via microsomal prostaglandin E2 synthase-1 (mPGES-1) blocking has been proven to be an important game changer in pharmaceutical industry in recent years. In this study, new chalcone derivative has been suc...

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Bibliographic Details

Main Authors:	Sanphetchaloemchok, Pitipat, Mohd Aluwi, Mohd Fadhlizil Fasihi, Rullah, Kamal, Wai, Lam Kok
Format:	Book Chapter
Language:	en en
Published:	Trans Tech Publications Ltd 2020
Subjects:	RS403 Materia Medica-Pharmaceutical Chemistry
Online Access:	http://irep.iium.edu.my/80242/1/80242_Synthesis%2C%20In%20silico%20molecular%20docking%20modeling.pdf http://irep.iium.edu.my/80242/2/80242_Synthesis%2C%20In%20silico%20molecular%20docking%20modeling_SCOPUS.pdf http://irep.iium.edu.my/80242/ https://www.scientific.net/MSF.981.247
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