Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii

Combination therapy is deployed for the treatment of multidrug-resistant Acinetobacter baumannii, as it can rapidly develop resistance to current antibiotics. This is the first study to investigate the synergistic effect of colistin/doripenem combination on the metabolome of A. baumannii. The met...

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Bibliographic Details

Main Authors:	Mahamad Maifiah, Mohd Hafidz, Creek, Darren J., Nation, Roger L., Forrest, Alan, Tsuji, Brian T., Velkov, Tony, Li, Jian
Format:	Article
Language:	en en
Published:	Springer Nature Limited. 2017
Subjects:	QR Microbiology RM Therapeutics. Pharmacology RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/65379/7/65379%20Untargeted%20metabolomics%20analysis%20reveals%20key%20pathways%20responsible.pdf http://irep.iium.edu.my/65379/8/65379%20Untargeted%20metabolomics%20analysis%20reveals%20key%20pathways%20responsible%20SCOPUS.pdf http://irep.iium.edu.my/65379/ https://www.nature.com/articles/srep45527.pdf
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