Prolonged infusion piperacillin-tazobactam decreases mortality and improves outcomes in severely ill patients: results of a systematic review and meta-analysis

Objective: Piperacillin-tazobactam is a commonly used antibiotic in critically ill patients; however, controversy exists as to whether mortality in serious infections can be decreased through administration by prolonged infusion compared with intermittent infusion. The purpose of this systematic...

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Main Authors:	Rhodes, Nathaniel J., Liu, Jiajun, O'Donnell, J. Nicholas, Dulhunty, Joel M., Abdul Aziz, Mohd. Hafiz, Berko, Patsy Y., Nadler, Barbara, Lipman, Jeffrey, Roberts, Jason A.
Format:	Article
Language:	en en en
Published:	The Society of Critical Care Medicine and Wolters Kluwer Health, Inc. 2018
Subjects:	RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid RM Therapeutics. Pharmacology RM300 Drugs and their action
Online Access:	http://irep.iium.edu.my/59246/1/59246_Prolonged%20infusion%20piperacillin-tazobactam.pdf http://irep.iium.edu.my/59246/2/59246_Prolonged%20infusion%20piperacillin-tazobactam_WOS.pdf http://irep.iium.edu.my/59246/13/59246_Prolonged%20infusion%20piperacillin-tazobactam%20decreases%20mortality%20and%20improves_SCOPUS.pdf http://irep.iium.edu.my/59246/ https://ovidsp.tx.ovid.com/sp-3.29.1a/ovidweb.cgi?WebLinkFrameset=1&S=JBOEFPBJCCDDMPGHNCEKMCJCJGJMAA00&returnUrl=ovidweb.cgi%3f%26Full%2bText%3dL%257cS.sh.22.23%257c0%257c00003246-201802000-00009%26S%3dJBOEFPBJCCDDMPGHNCEKMCJCJGJMAA00&directlink=https%3a%2f%2fovidsp.tx.ovid.com%2fovftpdfs%2fFPDDNCJCMCGHCC00%2ffs046%2fovft%2flive%2fgv023%2f00003246%2f00003246-201802000-00009.pdf&filename=Prolonged+Infusion+Piperacillin-Tazobactam+Decreases+Mortality+and+Improves+Outcomes+in+Severely+Ill+Patients%3a++Results+of+a+Systematic+Review+and+Meta-Analysis%2a.&pdf_key=FPDDNCJCMCGHCC00&pdf_index=/fs046/ovft/live/gv023/00003246/00003246-201802000-00009
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