Collagen production from animal husbandry for circular economy
Tissue regeneration in adult mammal does not occur spontaneously during wound healing but going through the process of remodelling and re-epidermisation of the tissue, resulting in contraction and scar formation. The extraction of collagen and fabrication of collagen scaffold are important to the ou...
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| Main Authors: | , , , |
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| Format: | Book Chapter |
| Language: | en en |
| Published: |
Springer
2024
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/119896/1/119896_Collagen%20production.pdf http://irep.iium.edu.my/119896/7/119896_Collagen%20production_SCOPUS.pdf http://irep.iium.edu.my/119896/ https://link.springer.com/chapter/10.1007/978-981-97-7010-6_3 |
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| Summary: | Tissue regeneration in adult mammal does not occur spontaneously during wound healing but going through the process of remodelling and re-epidermisation of the tissue, resulting in contraction and scar formation. The extraction of collagen and fabrication of collagen scaffold are important to the outcome of the treatment. The specific and important chemical analogues and properties in collagen can be
lost during the process of extraction and fabrication due to exposure to heat, moist and atmospheric condition. In this work, we looked into the details of extraction of collagen from bovine tendon, starting from the use of freeze drying to assist with swelling, the use of different concentrations of acetic acid to dialysis for 3–5 days and fabrication of collagen scaffold. From this work, we emphasis that the tiny details in
extraction and fabrication process of collagen scaffold are critical to the effectiveness of the outcome of regenerative scaffold. |
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