The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their use before meals on early colonizers single species biofilm
Abstract. – OBJECTIVE: The aim of the study was to determine the bacterial-adherence to the experimental pellicle pretreated with commer- cially available oral-rinse/photosensitizer (mim- icking use of oral-rinse/photosensitizer beforemeals). MATERIALS AND METHODS: An artificial mouth (NAM) syst...
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2022
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| Online Access: | http://irep.iium.edu.my/100310/1/100310_The%20effect%20of%20selected%20commercially.pdf http://irep.iium.edu.my/100310/2/100310_The%20effect%20of%20selected%20commercially_SCOPUS.pdf http://irep.iium.edu.my/100310/ https://www.europeanreview.org/wp/wp-content/uploads/5466-5475.pdf |
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| author | Zeeshan, Qamar Abdul, Nishath Sayed Khan, T.A. Zeeshan, Tayyaba Helal Uddin, A.B.M. Albaqawi, Ahmed Heji Almejlad, N.K. |
| author_facet | Zeeshan, Qamar Abdul, Nishath Sayed Khan, T.A. Zeeshan, Tayyaba Helal Uddin, A.B.M. Albaqawi, Ahmed Heji Almejlad, N.K. |
| author_sort | Zeeshan, Qamar |
| building | IIUM Library |
| collection | Institutional Repository |
| content_provider | International Islamic University Malaysia |
| content_source | IIUM Repository (IREP) |
| continent | Asia |
| country | Malaysia |
| description | Abstract. –
OBJECTIVE: The aim of the study was to determine the bacterial-adherence to the experimental pellicle pretreated with commer-
cially available oral-rinse/photosensitizer (mim- icking use of oral-rinse/photosensitizer beforemeals).
MATERIALS AND METHODS: An artificial mouth (NAM) system was used for the devel- opment of single-species biofilm (Actinomyces
viscosus, Sreptococcus mitis and Streptococ- cus sanguinis respectively). Two commercially available oral-rinses containing active ingredi-
ents [Essential oils (EO) and Chlorhexidine glu-conate (CHX) were used. Curcumin photosensi-tizer (PS) was used as a photosensitizer against
the microbes. For the adherence study, the ex-perimental pellicle on the beads (in the capillary tubes of the NAM system) was pretreated with
the oral-rinse and photosensitizer before the in-oculation of bacteria; this would resemble the use of rinse/photosensitizer before meal. The
bacterial population of the biofilm was determined using serial dilution assay and expressed as colony forming unit per ml. Deionized distilled water was used in place of oral-rinse/ photosensitizer and served as a negative-control. For the qualitative study, bacterial population
viewing was carried out using Scanning Electron Microscope (SEM).
RESULTS: It was observed that on treatment with the oral-rinses the bacterial population of S.mitis, S.sanguinis and A.viscosus (adherence)
was significantly reduced where the reduction was less for EO-based oral-rinse compared with that of CHX and curcumin PS in the following se-
quence EO<CHX<PS (p<0.05).
CONCLUSIONS: From the results, it appears that curcumin photosensitizer and oral-rinses contain CHX to be preferably used before-meal
and EO after-meal. |
| format | Article |
| id | my.iium.irep-100310 |
| institution | Universiti Islam Antarabangsa Malaysia |
| language | en en |
| publishDate | 2022 |
| publisher | NLM (Medline) |
| record_format | dspace |
| spelling | my.iium.irep-1003102022-09-30T07:05:05Z http://irep.iium.edu.my/100310/ The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their use before meals on early colonizers single species biofilm Zeeshan, Qamar Abdul, Nishath Sayed Khan, T.A. Zeeshan, Tayyaba Helal Uddin, A.B.M. Albaqawi, Ahmed Heji Almejlad, N.K. QD Chemistry RM Therapeutics. Pharmacology RS Pharmacy and materia medica RS192 Materia Medica-Pharmaceutical Technology RS403 Materia Medica-Pharmaceutical Chemistry Abstract. – OBJECTIVE: The aim of the study was to determine the bacterial-adherence to the experimental pellicle pretreated with commer- cially available oral-rinse/photosensitizer (mim- icking use of oral-rinse/photosensitizer beforemeals). MATERIALS AND METHODS: An artificial mouth (NAM) system was used for the devel- opment of single-species biofilm (Actinomyces viscosus, Sreptococcus mitis and Streptococ- cus sanguinis respectively). Two commercially available oral-rinses containing active ingredi- ents [Essential oils (EO) and Chlorhexidine glu-conate (CHX) were used. Curcumin photosensi-tizer (PS) was used as a photosensitizer against the microbes. For the adherence study, the ex-perimental pellicle on the beads (in the capillary tubes of the NAM system) was pretreated with the oral-rinse and photosensitizer before the in-oculation of bacteria; this would resemble the use of rinse/photosensitizer before meal. The bacterial population of the biofilm was determined using serial dilution assay and expressed as colony forming unit per ml. Deionized distilled water was used in place of oral-rinse/ photosensitizer and served as a negative-control. For the qualitative study, bacterial population viewing was carried out using Scanning Electron Microscope (SEM). RESULTS: It was observed that on treatment with the oral-rinses the bacterial population of S.mitis, S.sanguinis and A.viscosus (adherence) was significantly reduced where the reduction was less for EO-based oral-rinse compared with that of CHX and curcumin PS in the following se- quence EO<CHX<PS (p<0.05). CONCLUSIONS: From the results, it appears that curcumin photosensitizer and oral-rinses contain CHX to be preferably used before-meal and EO after-meal. NLM (Medline) 2022-07 Article PeerReviewed application/pdf en http://irep.iium.edu.my/100310/1/100310_The%20effect%20of%20selected%20commercially.pdf application/pdf en http://irep.iium.edu.my/100310/2/100310_The%20effect%20of%20selected%20commercially_SCOPUS.pdf Zeeshan, Qamar and Abdul, Nishath Sayed and Khan, T.A. and Zeeshan, Tayyaba and Helal Uddin, A.B.M. and Albaqawi, Ahmed Heji and Almejlad, N.K. (2022) The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their use before meals on early colonizers single species biofilm. European Review for Medical and Pharmacological Sciences, 26 (15). pp. 5466-5475. ISSN 1128-3602 https://www.europeanreview.org/wp/wp-content/uploads/5466-5475.pdf 10.26355/eurrev_202208_29415 |
| spellingShingle | QD Chemistry RM Therapeutics. Pharmacology RS Pharmacy and materia medica RS192 Materia Medica-Pharmaceutical Technology RS403 Materia Medica-Pharmaceutical Chemistry Zeeshan, Qamar Abdul, Nishath Sayed Khan, T.A. Zeeshan, Tayyaba Helal Uddin, A.B.M. Albaqawi, Ahmed Heji Almejlad, N.K. The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their use before meals on early colonizers single species biofilm |
| title | The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their
use before meals on early colonizers single species biofilm |
| title_full | The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their
use before meals on early colonizers single species biofilm |
| title_fullStr | The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their
use before meals on early colonizers single species biofilm |
| title_full_unstemmed | The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their
use before meals on early colonizers single species biofilm |
| title_short | The effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their
use before meals on early colonizers single species biofilm |
| title_sort | effect of selected commercially available mouth-rinses vs. curcumin photosensitizers in an artificial mouth model mimicking their
use before meals on early colonizers single species biofilm |
| topic | QD Chemistry RM Therapeutics. Pharmacology RS Pharmacy and materia medica RS192 Materia Medica-Pharmaceutical Technology RS403 Materia Medica-Pharmaceutical Chemistry |
| url | http://irep.iium.edu.my/100310/1/100310_The%20effect%20of%20selected%20commercially.pdf http://irep.iium.edu.my/100310/2/100310_The%20effect%20of%20selected%20commercially_SCOPUS.pdf http://irep.iium.edu.my/100310/ https://www.europeanreview.org/wp/wp-content/uploads/5466-5475.pdf |
| url_provider | http://irep.iium.edu.my/ |