A novel synthesis of anti-cancer drug gefitinib from 6,7-dimethoxy-3H-quinazolin-4-one
A novel synthesis of the anticancer drug gefitinib (Iressa) through novel alternative pathway has been successfully carried out. The synthesis was performed using 6,7-dimethoxy-3H-quinazolin-4-one as the starting material through four reaction stages: Chlorination, nucleophilic aromatic substitution...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | en |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2025
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| Online Access: | http://journalarticle.ukm.my/25630/1/SE%207.pdf http://journalarticle.ukm.my/25630/ https://www.ukm.my/jsm/english_journals/vol54num4_2025/contentsVol54num4_2025.html |
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