Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract
Antibiotic-resistant bacteria provide a great opportunity to use silver nanoparticles (AgNPs) as potential antibiotic replacements. This work utilized Stachytarpheta jamaicensis leaf extract (SJLE)-mediated electrosynthesis of biogenic AgNPs. By using two silver rods and SJLE as the electrolysis med...
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| Format: | Article |
| Language: | en |
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Penerbit Universiti Kebangsaan Malaysia
2024
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| Online Access: | http://journalarticle.ukm.my/24498/1/SS%2016.pdf http://journalarticle.ukm.my/24498/ https://www.ukm.my/jsm/english_journals/vol53num9_2024/contentsVol53num9_2024.html |
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| author | Hermanto, Dhony Ismillayli, Nurul Wiranatasari, Thiffany A. L. Mudasir, Mudasir Siswanta, Dwi Kuswandi, Bambang Siswoyo, iswoyo Suprapto, Suprapto Prasetyoko, Didik |
| author_facet | Hermanto, Dhony Ismillayli, Nurul Wiranatasari, Thiffany A. L. Mudasir, Mudasir Siswanta, Dwi Kuswandi, Bambang Siswoyo, iswoyo Suprapto, Suprapto Prasetyoko, Didik |
| author_sort | Hermanto, Dhony |
| building | Tun Sri Lanang Library |
| collection | Institutional Repository |
| content_provider | Universiti Kebangsaan Malaysia |
| content_source | UKM Journal Article Repository |
| continent | Asia |
| country | Malaysia |
| description | Antibiotic-resistant bacteria provide a great opportunity to use silver nanoparticles (AgNPs) as potential antibiotic replacements. This work utilized Stachytarpheta jamaicensis leaf extract (SJLE)-mediated electrosynthesis of biogenic AgNPs. By using two silver rods and SJLE as the electrolysis medium, biogenic AgNP is produced through electrosynthesis. The properties of the formed AgNPs and SJLE phytochemical composition were examined. The disc diffusion method was utilized to evaluate AgNPs’ antibacterial efficacy against Escherichia coli and Staphylococcus aureus. The high amount of phenolics, flavonoids, and tannins in SLJE provides biomolecules rich in -OH and carbonyl groups, allowing SLJE to have antimicrobial effects as well as act as a capping agent and bioreductor during electrosynthesis. The presence of functional groups from various phytochemicals leads to the formation of anisotropic AgNP crystals with a size of 38.22 ± 13.06 nm and high purity (95.75 ± 0.43%). Antibacterial activity tests against E. coli and S. aureus show that anisotropic biogenic AgNPs outperformed spherical AgNPs, probably due to the angular AgNPs’ ease of penetration into bacterial cell walls. The characteristics of the AgNPs developed induced outstanding antibacterial efficacy against E. coli and S. aureus. Thus, SLJE-based electrosynthesis provides a synergistic synthetic design of AgNPs as antibacterial agents with several potential long-term advantages, including high purity, fast synthesis, low cost, absence of hazardous ingredients, and simplicity in scaling up. |
| format | Article |
| id | my-ukm.journal.24498 |
| institution | Universiti Kebangsaan Malaysia |
| language | en |
| publishDate | 2024 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| record_format | eprints |
| spelling | my-ukm.journal.244982024-11-12T05:06:38Z http://journalarticle.ukm.my/24498/ Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract Hermanto, Dhony Ismillayli, Nurul Wiranatasari, Thiffany A. L. Mudasir, Mudasir Siswanta, Dwi Kuswandi, Bambang Siswoyo, iswoyo Suprapto, Suprapto Prasetyoko, Didik Antibiotic-resistant bacteria provide a great opportunity to use silver nanoparticles (AgNPs) as potential antibiotic replacements. This work utilized Stachytarpheta jamaicensis leaf extract (SJLE)-mediated electrosynthesis of biogenic AgNPs. By using two silver rods and SJLE as the electrolysis medium, biogenic AgNP is produced through electrosynthesis. The properties of the formed AgNPs and SJLE phytochemical composition were examined. The disc diffusion method was utilized to evaluate AgNPs’ antibacterial efficacy against Escherichia coli and Staphylococcus aureus. The high amount of phenolics, flavonoids, and tannins in SLJE provides biomolecules rich in -OH and carbonyl groups, allowing SLJE to have antimicrobial effects as well as act as a capping agent and bioreductor during electrosynthesis. The presence of functional groups from various phytochemicals leads to the formation of anisotropic AgNP crystals with a size of 38.22 ± 13.06 nm and high purity (95.75 ± 0.43%). Antibacterial activity tests against E. coli and S. aureus show that anisotropic biogenic AgNPs outperformed spherical AgNPs, probably due to the angular AgNPs’ ease of penetration into bacterial cell walls. The characteristics of the AgNPs developed induced outstanding antibacterial efficacy against E. coli and S. aureus. Thus, SLJE-based electrosynthesis provides a synergistic synthetic design of AgNPs as antibacterial agents with several potential long-term advantages, including high purity, fast synthesis, low cost, absence of hazardous ingredients, and simplicity in scaling up. Penerbit Universiti Kebangsaan Malaysia 2024 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/24498/1/SS%2016.pdf Hermanto, Dhony and Ismillayli, Nurul and Wiranatasari, Thiffany A. L. and Mudasir, Mudasir and Siswanta, Dwi and Kuswandi, Bambang and Siswoyo, iswoyo and Suprapto, Suprapto and Prasetyoko, Didik (2024) Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract. Sains Malaysiana, 53 (9). pp. 3113-3123. ISSN 0126-6039 https://www.ukm.my/jsm/english_journals/vol53num9_2024/contentsVol53num9_2024.html |
| spellingShingle | Hermanto, Dhony Ismillayli, Nurul Wiranatasari, Thiffany A. L. Mudasir, Mudasir Siswanta, Dwi Kuswandi, Bambang Siswoyo, iswoyo Suprapto, Suprapto Prasetyoko, Didik Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract |
| title | Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract |
| title_full | Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract |
| title_fullStr | Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract |
| title_full_unstemmed | Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract |
| title_short | Electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using Stachytarpheta jamaicensis leaf extract |
| title_sort | electrosynthesis of anisotropic biogenic silver nanoparticles as a promising antibacterial agent using stachytarpheta jamaicensis leaf extract |
| url | http://journalarticle.ukm.my/24498/1/SS%2016.pdf http://journalarticle.ukm.my/24498/ https://www.ukm.my/jsm/english_journals/vol53num9_2024/contentsVol53num9_2024.html |
| url_provider | http://journalarticle.ukm.my/ |