Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds
Azadirachta indica (neem) is an Asia native plant from Meliaceae family, which has been recognized for its pharmaceutical potential for ages and contain numerous bioactive phytochemicals with therapeutic potential. This research aims to examine the ethnomedicinal plants that have been recorded in tr...
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Penerbit Universiti Kebangsaan Malaysia
2024
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| Online Access: | http://journalarticle.ukm.my/23973/1/2-Razanah%2BRamya%2021-32.pdf http://journalarticle.ukm.my/23973/ https://spaj.ukm.my/ajehh/index.php/ajehh/index |
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| author | Razanah Ramya, Rashidi Othman, Farah Ayuni Mohd Hatta, Wan Syibrah Hanisah Wan Sulaiman, Nur Hanie Mohd Latiff, |
| author_facet | Razanah Ramya, Rashidi Othman, Farah Ayuni Mohd Hatta, Wan Syibrah Hanisah Wan Sulaiman, Nur Hanie Mohd Latiff, |
| author_sort | Razanah Ramya, |
| building | Tun Sri Lanang Library |
| collection | Institutional Repository |
| content_provider | Universiti Kebangsaan Malaysia |
| content_source | UKM Journal Article Repository |
| continent | Asia |
| country | Malaysia |
| description | Azadirachta indica (neem) is an Asia native plant from Meliaceae family, which has been recognized for its pharmaceutical potential for ages and contain numerous bioactive phytochemicals with therapeutic potential. This research aims to examine the ethnomedicinal plants that have been recorded in transliterated manuscripts and to discover the bioactive compounds. For methodology, secondary data were obtained from five selected Malay medical books. The experimental design involved two extraction methods, namely water extraction and sequential alkaline extraction. The data was qualitatively and quantitatively analyzed by Total Phenolic Content (TPC), and High-Performance Liquid Chromatography (HPLC). The findings from the Malay medical manuscript indicate that most diseases were physical illnesses. The total phenolic content of A. indica was 779.89 ± 12.32 μg GAE/g DW, and the phenolic acids detected by HPLC in both extractions were Vanillic acid, trans-p-coumaric acid, and ferulic acid. In conclusion, this study demonstrates that A. indica has a huge potential for further exploration in pharmaceuticals. |
| format | Article |
| id | my-ukm.journal.23973 |
| institution | Universiti Kebangsaan Malaysia |
| language | en |
| publishDate | 2024 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| record_format | eprints |
| spelling | my-ukm.journal.239732024-08-12T02:29:26Z http://journalarticle.ukm.my/23973/ Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds Razanah Ramya, Rashidi Othman, Farah Ayuni Mohd Hatta, Wan Syibrah Hanisah Wan Sulaiman, Nur Hanie Mohd Latiff, Azadirachta indica (neem) is an Asia native plant from Meliaceae family, which has been recognized for its pharmaceutical potential for ages and contain numerous bioactive phytochemicals with therapeutic potential. This research aims to examine the ethnomedicinal plants that have been recorded in transliterated manuscripts and to discover the bioactive compounds. For methodology, secondary data were obtained from five selected Malay medical books. The experimental design involved two extraction methods, namely water extraction and sequential alkaline extraction. The data was qualitatively and quantitatively analyzed by Total Phenolic Content (TPC), and High-Performance Liquid Chromatography (HPLC). The findings from the Malay medical manuscript indicate that most diseases were physical illnesses. The total phenolic content of A. indica was 779.89 ± 12.32 μg GAE/g DW, and the phenolic acids detected by HPLC in both extractions were Vanillic acid, trans-p-coumaric acid, and ferulic acid. In conclusion, this study demonstrates that A. indica has a huge potential for further exploration in pharmaceuticals. Penerbit Universiti Kebangsaan Malaysia 2024-06-30 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/23973/1/2-Razanah%2BRamya%2021-32.pdf Razanah Ramya, and Rashidi Othman, and Farah Ayuni Mohd Hatta, and Wan Syibrah Hanisah Wan Sulaiman, and Nur Hanie Mohd Latiff, (2024) Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds. Asian Journal of Environment, History and Heritage, 8 (1). pp. 21-32. ISSN 2590-4310 https://spaj.ukm.my/ajehh/index.php/ajehh/index |
| spellingShingle | Razanah Ramya, Rashidi Othman, Farah Ayuni Mohd Hatta, Wan Syibrah Hanisah Wan Sulaiman, Nur Hanie Mohd Latiff, Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds |
| title | Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds |
| title_full | Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds |
| title_fullStr | Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds |
| title_full_unstemmed | Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds |
| title_short | Azadirachta Indica (Semambu) in Traditional Malay Medical manuscripts and assessment of bioactive compounds |
| title_sort | azadirachta indica (semambu) in traditional malay medical manuscripts and assessment of bioactive compounds |
| url | http://journalarticle.ukm.my/23973/1/2-Razanah%2BRamya%2021-32.pdf http://journalarticle.ukm.my/23973/ https://spaj.ukm.my/ajehh/index.php/ajehh/index |
| url_provider | http://journalarticle.ukm.my/ |