Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus

Case of co-existence of twin pregnancy of complete hydatidiform molar with viable intrauterine pregnancy is extremely rare with low incidence of 1 case for 20,000 – 100,000. It is associated with high risk of spontaneous abortion, preterm delivery, intrauterine death, bleeding, pre-eclampsia,...

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Main Authors: Munirah Md Mansor, Khalidah MB, Dian Nasriana Nasuruddin, Hanita O
Format: Article
Language:en
Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2018
Online Access:http://journalarticle.ukm.my/20620/1/19_ms0219_pdf_11715.pdf
http://journalarticle.ukm.my/20620/
https://www.medicineandhealthukm.com/toc/13/2
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author Munirah Md Mansor,
Khalidah MB,
Dian Nasriana Nasuruddin,
Hanita O,
author_facet Munirah Md Mansor,
Khalidah MB,
Dian Nasriana Nasuruddin,
Hanita O,
author_sort Munirah Md Mansor,
building Tun Sri Lanang Library
collection Institutional Repository
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
continent Asia
country Malaysia
description Case of co-existence of twin pregnancy of complete hydatidiform molar with viable intrauterine pregnancy is extremely rare with low incidence of 1 case for 20,000 – 100,000. It is associated with high risk of spontaneous abortion, preterm delivery, intrauterine death, bleeding, pre-eclampsia, and persistence trophoblastic disease (PTD). It may associate with biochemical derangement that may induce symptomatic manifestation to the mother. There are few cases reported in Asia population with significant clinical dilemma and management to the maternal and foetus. Here, we report a case of a young woman with previous bad obstetric history who presented with antepartum per-vaginal bleeding and was noted to have a twin pregnancy with complete hydatidiform molar and viable foetus. It was complicated with markedly elevated human chorionic gonadotropin (hCG) and hyperthyroidism. Postpartumly, her hCG level was persistently high and her condition progressed into gestational trophoblastic neoplasm.
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institution Universiti Kebangsaan Malaysia
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spelling my-ukm.journal.206202022-11-28T13:11:33Z http://journalarticle.ukm.my/20620/ Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus Munirah Md Mansor, Khalidah MB, Dian Nasriana Nasuruddin, Hanita O, Case of co-existence of twin pregnancy of complete hydatidiform molar with viable intrauterine pregnancy is extremely rare with low incidence of 1 case for 20,000 – 100,000. It is associated with high risk of spontaneous abortion, preterm delivery, intrauterine death, bleeding, pre-eclampsia, and persistence trophoblastic disease (PTD). It may associate with biochemical derangement that may induce symptomatic manifestation to the mother. There are few cases reported in Asia population with significant clinical dilemma and management to the maternal and foetus. Here, we report a case of a young woman with previous bad obstetric history who presented with antepartum per-vaginal bleeding and was noted to have a twin pregnancy with complete hydatidiform molar and viable foetus. It was complicated with markedly elevated human chorionic gonadotropin (hCG) and hyperthyroidism. Postpartumly, her hCG level was persistently high and her condition progressed into gestational trophoblastic neoplasm. Pusat Perubatan Universiti Kebangsaan Malaysia 2018-12 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/20620/1/19_ms0219_pdf_11715.pdf Munirah Md Mansor, and Khalidah MB, and Dian Nasriana Nasuruddin, and Hanita O, (2018) Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus. Medicine & Health, 13 (2). pp. 180-187. ISSN 2289-5728 https://www.medicineandhealthukm.com/toc/13/2
spellingShingle Munirah Md Mansor,
Khalidah MB,
Dian Nasriana Nasuruddin,
Hanita O,
Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus
title Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus
title_full Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus
title_fullStr Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus
title_full_unstemmed Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus
title_short Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus
title_sort biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus
url http://journalarticle.ukm.my/20620/1/19_ms0219_pdf_11715.pdf
http://journalarticle.ukm.my/20620/
https://www.medicineandhealthukm.com/toc/13/2
url_provider http://journalarticle.ukm.my/