Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum
Melastoma malabathricum or Senduduk Putih is one of the herbs listed under National Key Economic Area (NKEA) of Malaysia. It has the potential to be used as remedies that is rich in natural flavonoids. One of the innovations for extraction in modern technology is Ultrasound-Assisted Extraction (UA...
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| Format: | Article |
| Language: | en |
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Penerbit Universiti Kebangsaan Malaysia
2019
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| Online Access: | http://journalarticle.ukm.my/19601/1/12.pdf http://journalarticle.ukm.my/19601/ https://www.ukm.my/jkukm/si-21-2019/ |
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| author | Lee, Chia Hau Lee, Ting Hun Harisun Ya’akob, Wong, Syieluing Jannet, Hichem Ben |
| author_facet | Lee, Chia Hau Lee, Ting Hun Harisun Ya’akob, Wong, Syieluing Jannet, Hichem Ben |
| author_sort | Lee, Chia Hau |
| building | Tun Sri Lanang Library |
| collection | Institutional Repository |
| content_provider | Universiti Kebangsaan Malaysia |
| content_source | UKM Journal Article Repository |
| continent | Asia |
| country | Malaysia |
| description | Melastoma malabathricum or Senduduk Putih is one of the herbs listed under National Key Economic Area (NKEA) of
Malaysia. It has the potential to be used as remedies that is rich in natural flavonoids. One of the innovations for extraction
in modern technology is Ultrasound-Assisted Extraction (UAE) that showed several advantages. Therefore, this study aimed
to explore using UAE to extract the total flavonoids in M. malabathricum. After that, UAE is optimized coupled with a stirrer
for total flavonoid extraction. Five operating parameters: ethanol concentration, plant material to solvent ratio, extraction
temperature, extraction time and ultrasound power were investigated by one-factor-at-a-time (OFAT) method to choose the
most important parameters. After that, the response surface methodology coupled with face-centered central composite
design (FCCD) was employed to study the interaction of the three keys parameters. The optimized conditions to extract total
flavonoids content by UAE with constant mixing speed (300 ± 6 rpm) were at a ratio of 1g of plant material: 30 mL of 100%
(v/v) ethanol, extraction temperature at 70oC, 19 min of extraction time and 280 W of ultrasound power. The experimental
yields of total flavonoids content were 64.94 mg/g, which is well matched with the predicted value of 63.75 mg/g. |
| format | Article |
| id | my-ukm.journal.19601 |
| institution | Universiti Kebangsaan Malaysia |
| language | en |
| publishDate | 2019 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| record_format | eprints |
| spelling | my-ukm.journal.196012022-09-08T02:56:15Z http://journalarticle.ukm.my/19601/ Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum Lee, Chia Hau Lee, Ting Hun Harisun Ya’akob, Wong, Syieluing Jannet, Hichem Ben Melastoma malabathricum or Senduduk Putih is one of the herbs listed under National Key Economic Area (NKEA) of Malaysia. It has the potential to be used as remedies that is rich in natural flavonoids. One of the innovations for extraction in modern technology is Ultrasound-Assisted Extraction (UAE) that showed several advantages. Therefore, this study aimed to explore using UAE to extract the total flavonoids in M. malabathricum. After that, UAE is optimized coupled with a stirrer for total flavonoid extraction. Five operating parameters: ethanol concentration, plant material to solvent ratio, extraction temperature, extraction time and ultrasound power were investigated by one-factor-at-a-time (OFAT) method to choose the most important parameters. After that, the response surface methodology coupled with face-centered central composite design (FCCD) was employed to study the interaction of the three keys parameters. The optimized conditions to extract total flavonoids content by UAE with constant mixing speed (300 ± 6 rpm) were at a ratio of 1g of plant material: 30 mL of 100% (v/v) ethanol, extraction temperature at 70oC, 19 min of extraction time and 280 W of ultrasound power. The experimental yields of total flavonoids content were 64.94 mg/g, which is well matched with the predicted value of 63.75 mg/g. Penerbit Universiti Kebangsaan Malaysia 2019 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/19601/1/12.pdf Lee, Chia Hau and Lee, Ting Hun and Harisun Ya’akob, and Wong, Syieluing and Jannet, Hichem Ben (2019) Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum. Jurnal Kejuruteraan, 2 (1(SI)). pp. 91-102. ISSN 0128-0198 https://www.ukm.my/jkukm/si-21-2019/ |
| spellingShingle | Lee, Chia Hau Lee, Ting Hun Harisun Ya’akob, Wong, Syieluing Jannet, Hichem Ben Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum |
| title | Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum |
| title_full | Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum |
| title_fullStr | Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum |
| title_full_unstemmed | Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum |
| title_short | Optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of Melastoma Malabathricum |
| title_sort | optimization of ultrasound-assisted extraction of total flavonoids content from the white flowering variety of melastoma malabathricum |
| url | http://journalarticle.ukm.my/19601/1/12.pdf http://journalarticle.ukm.my/19601/ https://www.ukm.my/jkukm/si-21-2019/ |
| url_provider | http://journalarticle.ukm.my/ |