Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases

Psychotropic polypharmacy among elderly patients is problematic due to their multiple comorbidities. This study investigated psychotropic polypharmacy among elderly patients discharged from a Malaysian university hospital and its associated factors. Discharges of patients aged 65 years or abov...

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Main Authors: Woon, Luke Sy-Cherng, Gan, LLY
Format: Article
Language:en
Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2021
Online Access:http://journalarticle.ukm.my/18281/1/19_ms0532_pdf_30239.pdf
http://journalarticle.ukm.my/18281/
https://medicineandhealthukm.com/toc/16/2
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author Woon, Luke Sy-Cherng
Gan, LLY
author_facet Woon, Luke Sy-Cherng
Gan, LLY
author_sort Woon, Luke Sy-Cherng
building Tun Sri Lanang Library
collection Institutional Repository
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
continent Asia
country Malaysia
description Psychotropic polypharmacy among elderly patients is problematic due to their multiple comorbidities. This study investigated psychotropic polypharmacy among elderly patients discharged from a Malaysian university hospital and its associated factors. Discharges of patients aged 65 years or above from the psychiatric wards from 2010 to 2019 were reviewed. Sociodemographic data, length of stay (LOS), psychiatric and other diagnoses, and psychotropic prescription upon discharge were extracted from electronic databases. Multiple logistic regression was conducted with age, gender, race, marital status, main psychiatric diagnosis, LOS, and the number of medical comorbidities as independent variables, and polypharmacy (>2 psychotropics) as the dependent variable. There were 354 discharges in this period. The mean age was 72.4 years (SD=5.9 years); 63.0% were female and 39.8% were Malays. Most were married (84.2%). The commonest category of psychiatric diagnosis was mood disorders (54.5%). A total of 76.8% of the discharges involved one or more medical comorbidities. The median number of psychotropics was two, with 38.1% prescribed three or more psychotropics. In the multiple regression model, female gender, Malay race, and being married were significantly associated with psychotropic polypharmacy. Sociocultural factors may contribute to psychotropic polypharmacy among elderly patients. Such factors require further investigations to elucidate their roles.
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spelling my-ukm.journal.182812022-03-25T01:54:47Z http://journalarticle.ukm.my/18281/ Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases Woon, Luke Sy-Cherng Gan, LLY Psychotropic polypharmacy among elderly patients is problematic due to their multiple comorbidities. This study investigated psychotropic polypharmacy among elderly patients discharged from a Malaysian university hospital and its associated factors. Discharges of patients aged 65 years or above from the psychiatric wards from 2010 to 2019 were reviewed. Sociodemographic data, length of stay (LOS), psychiatric and other diagnoses, and psychotropic prescription upon discharge were extracted from electronic databases. Multiple logistic regression was conducted with age, gender, race, marital status, main psychiatric diagnosis, LOS, and the number of medical comorbidities as independent variables, and polypharmacy (>2 psychotropics) as the dependent variable. There were 354 discharges in this period. The mean age was 72.4 years (SD=5.9 years); 63.0% were female and 39.8% were Malays. Most were married (84.2%). The commonest category of psychiatric diagnosis was mood disorders (54.5%). A total of 76.8% of the discharges involved one or more medical comorbidities. The median number of psychotropics was two, with 38.1% prescribed three or more psychotropics. In the multiple regression model, female gender, Malay race, and being married were significantly associated with psychotropic polypharmacy. Sociocultural factors may contribute to psychotropic polypharmacy among elderly patients. Such factors require further investigations to elucidate their roles. Pusat Perubatan Universiti Kebangsaan Malaysia 2021-12 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/18281/1/19_ms0532_pdf_30239.pdf Woon, Luke Sy-Cherng and Gan, LLY (2021) Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases. Medicine & Health, 16 (2). pp. 249-262. ISSN 2289-5728 https://medicineandhealthukm.com/toc/16/2
spellingShingle Woon, Luke Sy-Cherng
Gan, LLY
Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases
title Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases
title_full Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases
title_fullStr Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases
title_full_unstemmed Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases
title_short Psychotropic polypharmacy among elderly patients with mental illness in a Malaysian university hospital : a 10-year review of hospital databases
title_sort psychotropic polypharmacy among elderly patients with mental illness in a malaysian university hospital : a 10-year review of hospital databases
url http://journalarticle.ukm.my/18281/1/19_ms0532_pdf_30239.pdf
http://journalarticle.ukm.my/18281/
https://medicineandhealthukm.com/toc/16/2
url_provider http://journalarticle.ukm.my/