Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract

Arumanis mango is one of plants potentially used as a medicine. Arumanis mango leaf is potentially used as antimicrobial, which are as antibacterial and antifungal. Mango leaf extracts are able to inhibit Candida albicans with inhibition zone of 8.12 mm. The use of extracts for various purposes has...

Full description

Saved in:
Bibliographic Details
Main Authors: Dian Riana Ningsih, Purwati, Zusfahair, Filliani Akanadewi
Format: Article
Language:en
Published: Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:http://journalarticle.ukm.my/14344/1/11%20Dian%20Riana%20Ningsih.pdf
http://journalarticle.ukm.my/14344/
http://www.ukm.my/jsm/malay_journals/jilid48bil9_2019/KandunganJilid48Bil9_2019.html
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1834432388517593088
author Dian Riana Ningsih,
Purwati,
Zusfahair,
Filliani Akanadewi,
author_facet Dian Riana Ningsih,
Purwati,
Zusfahair,
Filliani Akanadewi,
author_sort Dian Riana Ningsih,
building Tun Sri Lanang Library
collection Institutional Repository
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
continent Asia
country Malaysia
description Arumanis mango is one of plants potentially used as a medicine. Arumanis mango leaf is potentially used as antimicrobial, which are as antibacterial and antifungal. Mango leaf extracts are able to inhibit Candida albicans with inhibition zone of 8.12 mm. The use of extracts for various purposes has disadvantages. This research aims to formulate ointments dosage from mango leaf extracts, to know its physical properties and its activity against Candida albicans. Antifungal activity test is conducted using diffusion method. The fungus used is Candida albicans. The absorbent ointment preparations has homogeneous semisolid form, yellowish white color, and distinctive odor. The ointment preparations has dispersive power value of 4.90-6.23 cm, adhesiveness of 2.0-7.0 seconds, pH value of 6.56-6.99 and able to protect skin from the outside environment. Inhibition zone of absorbent ointment with concentrations of 30, 65, and 125 ppm, respectively, was 3.07; 5.96; and 9.51 mm.
format Article
id my-ukm.journal.14344
institution Universiti Kebangsaan Malaysia
language en
publishDate 2019
publisher Penerbit Universiti Kebangsaan Malaysia
record_format eprints
spelling my-ukm.journal.143442020-03-03T08:00:17Z http://journalarticle.ukm.my/14344/ Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract Dian Riana Ningsih, Purwati, Zusfahair, Filliani Akanadewi, Arumanis mango is one of plants potentially used as a medicine. Arumanis mango leaf is potentially used as antimicrobial, which are as antibacterial and antifungal. Mango leaf extracts are able to inhibit Candida albicans with inhibition zone of 8.12 mm. The use of extracts for various purposes has disadvantages. This research aims to formulate ointments dosage from mango leaf extracts, to know its physical properties and its activity against Candida albicans. Antifungal activity test is conducted using diffusion method. The fungus used is Candida albicans. The absorbent ointment preparations has homogeneous semisolid form, yellowish white color, and distinctive odor. The ointment preparations has dispersive power value of 4.90-6.23 cm, adhesiveness of 2.0-7.0 seconds, pH value of 6.56-6.99 and able to protect skin from the outside environment. Inhibition zone of absorbent ointment with concentrations of 30, 65, and 125 ppm, respectively, was 3.07; 5.96; and 9.51 mm. Penerbit Universiti Kebangsaan Malaysia 2019-09 Article NonPeerReviewed application/pdf en http://journalarticle.ukm.my/14344/1/11%20Dian%20Riana%20Ningsih.pdf Dian Riana Ningsih, and Purwati, and Zusfahair, and Filliani Akanadewi, (2019) Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract. Sains Malaysiana, 48 (9). pp. 1907-1912. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid48bil9_2019/KandunganJilid48Bil9_2019.html
spellingShingle Dian Riana Ningsih,
Purwati,
Zusfahair,
Filliani Akanadewi,
Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract
title Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract
title_full Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract
title_fullStr Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract
title_full_unstemmed Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract
title_short Formulation and evaluation of natural anti Candida albicans ointment containing mango leaf (Mangifera indica L.) extract
title_sort formulation and evaluation of natural anti candida albicans ointment containing mango leaf (mangifera indica l.) extract
url http://journalarticle.ukm.my/14344/1/11%20Dian%20Riana%20Ningsih.pdf
http://journalarticle.ukm.my/14344/
http://www.ukm.my/jsm/malay_journals/jilid48bil9_2019/KandunganJilid48Bil9_2019.html
url_provider http://journalarticle.ukm.my/