A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery

We compared the analgesic profile between patient-controlled analgesia (PCA) using oxycodone and morphine in post total abdominal hysterectomy patients. Eighty-four ASA I or II patients, aged 18 to 65 years who underwent total abdominal hysterectomy were recruited into this prospective, double blind...

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Main Authors: Chen JL, Rufinah T, Fadzlon Mohd Yatim, Liu, Chian Yong, Omar S, Mahazir K
Format: Article
Language:en
Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2018
Online Access:http://journalarticle.ukm.my/12563/1/4.chen_jl_et_al.pdf
http://journalarticle.ukm.my/12563/
http://jsurgacad.com/toc
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author Chen JL,
Rufinah T,
Fadzlon Mohd Yatim,
Liu, Chian Yong
Omar S,
Mahazir K,
author_facet Chen JL,
Rufinah T,
Fadzlon Mohd Yatim,
Liu, Chian Yong
Omar S,
Mahazir K,
author_sort Chen JL,
building Tun Sri Lanang Library
collection Institutional Repository
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
continent Asia
country Malaysia
description We compared the analgesic profile between patient-controlled analgesia (PCA) using oxycodone and morphine in post total abdominal hysterectomy patients. Eighty-four ASA I or II patients, aged 18 to 65 years who underwent total abdominal hysterectomy were recruited into this prospective, double blind, randomised controlled study. They were randomised to receive either PCA oxycodone 0.7 mg per bolus or PCA morphine 1 mg per bolus for postoperative pain relief. At the end of surgery, all patients received IV morphine 0.1 mg/kg and skin incision was infiltrated with 20 mls of bupivacaine 0.25%. Post-operative pain scores, opioids consumptions, sedation scores and side effects were assessed upon arrival and at 30 minutes after arrival to recovery area, as well as at 6 hours and 24 hours after the operation in the ward. Patients’ overall satisfaction was also assessed 24 hours postoperatively.No significant differences were observed in terms of postoperative pain scores, opioids consumption, sedation scores, side effects as well as patient’s overall satisfaction between the PCA oxycodone and PCA morphine group. Oxycodone was comparable to morphine as PCA in terms of total opioid consumption, pain scores and satisfaction level for patients undergoing total abdominal hysterectomy and therefore may be an alternative to morphine in postoperative pain management as PCA.
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institution Universiti Kebangsaan Malaysia
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publisher Pusat Perubatan Universiti Kebangsaan Malaysia
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spelling my-ukm.journal.125632019-02-14T21:41:49Z http://journalarticle.ukm.my/12563/ A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery Chen JL, Rufinah T, Fadzlon Mohd Yatim, Liu, Chian Yong Omar S, Mahazir K, We compared the analgesic profile between patient-controlled analgesia (PCA) using oxycodone and morphine in post total abdominal hysterectomy patients. Eighty-four ASA I or II patients, aged 18 to 65 years who underwent total abdominal hysterectomy were recruited into this prospective, double blind, randomised controlled study. They were randomised to receive either PCA oxycodone 0.7 mg per bolus or PCA morphine 1 mg per bolus for postoperative pain relief. At the end of surgery, all patients received IV morphine 0.1 mg/kg and skin incision was infiltrated with 20 mls of bupivacaine 0.25%. Post-operative pain scores, opioids consumptions, sedation scores and side effects were assessed upon arrival and at 30 minutes after arrival to recovery area, as well as at 6 hours and 24 hours after the operation in the ward. Patients’ overall satisfaction was also assessed 24 hours postoperatively.No significant differences were observed in terms of postoperative pain scores, opioids consumption, sedation scores, side effects as well as patient’s overall satisfaction between the PCA oxycodone and PCA morphine group. Oxycodone was comparable to morphine as PCA in terms of total opioid consumption, pain scores and satisfaction level for patients undergoing total abdominal hysterectomy and therefore may be an alternative to morphine in postoperative pain management as PCA. Pusat Perubatan Universiti Kebangsaan Malaysia 2018 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12563/1/4.chen_jl_et_al.pdf Chen JL, and Rufinah T, and Fadzlon Mohd Yatim, and Liu, Chian Yong and Omar S, and Mahazir K, (2018) A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery. Journal of Surgical Academia, 8 (2). pp. 17-22. ISSN 2231-7481 http://jsurgacad.com/toc
spellingShingle Chen JL,
Rufinah T,
Fadzlon Mohd Yatim,
Liu, Chian Yong
Omar S,
Mahazir K,
A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_full A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_fullStr A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_full_unstemmed A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_short A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_sort comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
url http://journalarticle.ukm.my/12563/1/4.chen_jl_et_al.pdf
http://journalarticle.ukm.my/12563/
http://jsurgacad.com/toc
url_provider http://journalarticle.ukm.my/