Synthesis, characterization and antibacterial activity of mono-, di- and tri-tosylate of glycerol
Glycerol is a valuable co-product from oleochemical industry such as from fatty acid and biodiesel production. By having three hydroxyl groups in its molecule, glycerol can undergo chemical modifications that lead to many possible applications. This paper reports the tosylation process of glycerol w...
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| Language: | en |
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Penerbit Universiti Kebangsaan Malaysia
2016
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| Online Access: | http://journalarticle.ukm.my/9753/1/16_Yusrabbil_Amiyati_Yusof.pdf http://journalarticle.ukm.my/9753/ http://www.ukm.my/jsm/malay_journals/jilid45bil4_2016/KandunganJilid45Bil4_2016.htm |
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| author | Yusrabbil Amiyati Yusof, Azhar Ariffin A., |
| author_facet | Yusrabbil Amiyati Yusof, Azhar Ariffin A., |
| author_sort | Yusrabbil Amiyati Yusof, |
| building | Tun Sri Lanang Library |
| collection | Institutional Repository |
| content_provider | Universiti Kebangsaan Malaysia |
| content_source | UKM Journal Article Repository |
| continent | Asia |
| country | Malaysia |
| description | Glycerol is a valuable co-product from oleochemical industry such as from fatty acid and biodiesel production. By having three hydroxyl groups in its molecule, glycerol can undergo chemical modifications that lead to many possible applications. This paper reports the tosylation process of glycerol with para-toluenesulfonyl chloride (p-TsCl). Reaction of glycerol with p-TsCl in the presence of a base produced mono-, di- and tri-tosylate of glycerol even though the reaction was carried out at the mole ratio of 1.2:1.0 of glycerol to p-TsCl. The compounds were successfully isolated and characterized. Mono-, di- and tri-tosylate of glycerol exhibited inhibitory activity against Staphylococcus aureus (gram positive bacteria) and Pseudomonas aeruginosa (gram negative bacteria). |
| format | Article |
| id | my-ukm.journal-9753 |
| institution | Universiti Kebangsaan Malaysia |
| language | en |
| publishDate | 2016 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| record_format | eprints |
| spelling | my-ukm.journal-97532016-12-14T06:50:44Z http://journalarticle.ukm.my/9753/ Synthesis, characterization and antibacterial activity of mono-, di- and tri-tosylate of glycerol Yusrabbil Amiyati Yusof, Azhar Ariffin A., Glycerol is a valuable co-product from oleochemical industry such as from fatty acid and biodiesel production. By having three hydroxyl groups in its molecule, glycerol can undergo chemical modifications that lead to many possible applications. This paper reports the tosylation process of glycerol with para-toluenesulfonyl chloride (p-TsCl). Reaction of glycerol with p-TsCl in the presence of a base produced mono-, di- and tri-tosylate of glycerol even though the reaction was carried out at the mole ratio of 1.2:1.0 of glycerol to p-TsCl. The compounds were successfully isolated and characterized. Mono-, di- and tri-tosylate of glycerol exhibited inhibitory activity against Staphylococcus aureus (gram positive bacteria) and Pseudomonas aeruginosa (gram negative bacteria). Penerbit Universiti Kebangsaan Malaysia 2016-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9753/1/16_Yusrabbil_Amiyati_Yusof.pdf Yusrabbil Amiyati Yusof, and Azhar Ariffin A., (2016) Synthesis, characterization and antibacterial activity of mono-, di- and tri-tosylate of glycerol. Sains Malaysiana, 45 (4). pp. 621-625. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid45bil4_2016/KandunganJilid45Bil4_2016.htm |
| spellingShingle | Yusrabbil Amiyati Yusof, Azhar Ariffin A., Synthesis, characterization and antibacterial activity of mono-, di- and tri-tosylate of glycerol |
| title | Synthesis, characterization and antibacterial activity of mono-,
di- and tri-tosylate of glycerol |
| title_full | Synthesis, characterization and antibacterial activity of mono-,
di- and tri-tosylate of glycerol |
| title_fullStr | Synthesis, characterization and antibacterial activity of mono-,
di- and tri-tosylate of glycerol |
| title_full_unstemmed | Synthesis, characterization and antibacterial activity of mono-,
di- and tri-tosylate of glycerol |
| title_short | Synthesis, characterization and antibacterial activity of mono-,
di- and tri-tosylate of glycerol |
| title_sort | synthesis, characterization and antibacterial activity of mono-,
di- and tri-tosylate of glycerol |
| url | http://journalarticle.ukm.my/9753/1/16_Yusrabbil_Amiyati_Yusof.pdf http://journalarticle.ukm.my/9753/ http://www.ukm.my/jsm/malay_journals/jilid45bil4_2016/KandunganJilid45Bil4_2016.htm |
| url_provider | http://journalarticle.ukm.my/ |