Extra-gonadal germ cell tumour – what about the testis!
Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature as in a majority of them, a primary source is...
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| Format: | Article |
| Language: | en |
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Department of Surgery, UKM Medical Centre
2011
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| Online Access: | http://journalarticle.ukm.my/807/1/34-36.pdf http://journalarticle.ukm.my/807/ http://jsurgacad.com/ |
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| _version_ | 1831353083227013120 |
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| author | Johann FK, Praveen S, Christopher CKH, Goh EH, Razman J, Zulkifli MZ, |
| author_facet | Johann FK, Praveen S, Christopher CKH, Goh EH, Razman J, Zulkifli MZ, |
| author_sort | Johann FK, |
| building | Tun Sri Lanang Library |
| collection | Institutional Repository |
| content_provider | Universiti Kebangsaan Malaysia |
| content_source | UKM Journal Article Repository |
| continent | Asia |
| country | Malaysia |
| description | Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature as in a majority of them, a primary source is found in the testis, thus representing a metastatic gonadal tumour. The testis pathology could be either a true germ cell foci, an intra-tubular epithelial neoplasia or an area of fibrosis, indicating a „burnt out tumour‟. We report a 39-year-old male who underwent laparotomy and excision of a retroperitoneal tumour. Histopathological examination revealed retroperitoneal lymph node of mixed germ cell tumour origin. Clinical and ultrasound examination of bilateral testis was normal. The patient refused orchidectomy or a testicular biopsy. He underwent four cycles of bleomycin, cisplatin, and etoposide with no evidence of tumour recurrence on follow up and remains disease free after 12 months of diagnosis. A literature review of EGGCT, its relation and factors relating with future testicular tumour is presented. |
| format | Article |
| id | my-ukm.journal-807 |
| institution | Universiti Kebangsaan Malaysia |
| language | en |
| publishDate | 2011 |
| publisher | Department of Surgery, UKM Medical Centre |
| record_format | eprints |
| spelling | my-ukm.journal-8072016-12-14T06:28:14Z http://journalarticle.ukm.my/807/ Extra-gonadal germ cell tumour – what about the testis! Johann FK, Praveen S, Christopher CKH, Goh EH, Razman J, Zulkifli MZ, Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature as in a majority of them, a primary source is found in the testis, thus representing a metastatic gonadal tumour. The testis pathology could be either a true germ cell foci, an intra-tubular epithelial neoplasia or an area of fibrosis, indicating a „burnt out tumour‟. We report a 39-year-old male who underwent laparotomy and excision of a retroperitoneal tumour. Histopathological examination revealed retroperitoneal lymph node of mixed germ cell tumour origin. Clinical and ultrasound examination of bilateral testis was normal. The patient refused orchidectomy or a testicular biopsy. He underwent four cycles of bleomycin, cisplatin, and etoposide with no evidence of tumour recurrence on follow up and remains disease free after 12 months of diagnosis. A literature review of EGGCT, its relation and factors relating with future testicular tumour is presented. Department of Surgery, UKM Medical Centre 2011-04-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/807/1/34-36.pdf Johann FK, and Praveen S, and Christopher CKH, and Goh EH, and Razman J, and Zulkifli MZ, (2011) Extra-gonadal germ cell tumour – what about the testis! Journal of Surgical Academia, 1 (1). pp. 34-36. ISSN 2231-7481 http://jsurgacad.com/ |
| spellingShingle | Johann FK, Praveen S, Christopher CKH, Goh EH, Razman J, Zulkifli MZ, Extra-gonadal germ cell tumour – what about the testis! |
| title | Extra-gonadal germ cell tumour – what about the testis! |
| title_full | Extra-gonadal germ cell tumour – what about the testis! |
| title_fullStr | Extra-gonadal germ cell tumour – what about the testis! |
| title_full_unstemmed | Extra-gonadal germ cell tumour – what about the testis! |
| title_short | Extra-gonadal germ cell tumour – what about the testis! |
| title_sort | extra-gonadal germ cell tumour – what about the testis! |
| url | http://journalarticle.ukm.my/807/1/34-36.pdf http://journalarticle.ukm.my/807/ http://jsurgacad.com/ |
| url_provider | http://journalarticle.ukm.my/ |