Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats
Ficus deltoidea or Mas cotek is one of the common medicinal plants used in Malaysia has been claimed to have antidiabetic activity. However, scientific evidence to confirm its efficacy is still lacking. Thus, the present study was undertaken to evaluate the potential of ethanolic extract of Ficus de...
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| Format: | Article |
| Language: | en |
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Penerbit UKM
2010
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| Online Access: | http://journalarticle.ukm.my/3661/1/Antihyperglycemic_and_Glucose_Tolerance_Activity.pdf http://journalarticle.ukm.my/3661/ http://www.fsk.ukm.my/jurnal/jilid%208%281%29%202010/Bab%205.pdf |
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| _version_ | 1831354936140496896 |
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| author | Zainah Adam, Muhajir Hamid, Amin Ismail, Shafii Khamis, Norazizah Marsidi, |
| author_facet | Zainah Adam, Muhajir Hamid, Amin Ismail, Shafii Khamis, Norazizah Marsidi, |
| author_sort | Zainah Adam, |
| building | Tun Sri Lanang Library |
| collection | Institutional Repository |
| content_provider | Universiti Kebangsaan Malaysia |
| content_source | UKM Journal Article Repository |
| continent | Asia |
| country | Malaysia |
| description | Ficus deltoidea or Mas cotek is one of the common medicinal plants used in Malaysia has been claimed to have antidiabetic activity. However, scientific evidence to confirm its efficacy is still lacking. Thus, the present study was undertaken to evaluate the potential of ethanolic extract of Ficus deltoidea to reduce hyperglycaemia in streptozotocininduced diabetic rats at different prandial state. The results showed that, ethanolic extract of Ficus deltoidea significantly reduced fasting and postprandial hyperglycemia particularly after 4 and 6 hours of extract administration. Likewise, glucose tolerance activity was significantly improved in the presence of Ficus deltoidea ethanolic extract at a low dose, 100 mg/kg. It is suggested that ethanolic extract of Ficus deltoidea at particular doses, possess fasting and postprandial antihyperglycemic activity as well as glucose tolerance activity in streptozotocin-induced diabetic rats. |
| format | Article |
| id | my-ukm.journal-3661 |
| institution | Universiti Kebangsaan Malaysia |
| language | en |
| publishDate | 2010 |
| publisher | Penerbit UKM |
| record_format | eprints |
| spelling | my-ukm.journal-36612016-12-14T06:35:03Z http://journalarticle.ukm.my/3661/ Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats Zainah Adam, Muhajir Hamid, Amin Ismail, Shafii Khamis, Norazizah Marsidi, Ficus deltoidea or Mas cotek is one of the common medicinal plants used in Malaysia has been claimed to have antidiabetic activity. However, scientific evidence to confirm its efficacy is still lacking. Thus, the present study was undertaken to evaluate the potential of ethanolic extract of Ficus deltoidea to reduce hyperglycaemia in streptozotocininduced diabetic rats at different prandial state. The results showed that, ethanolic extract of Ficus deltoidea significantly reduced fasting and postprandial hyperglycemia particularly after 4 and 6 hours of extract administration. Likewise, glucose tolerance activity was significantly improved in the presence of Ficus deltoidea ethanolic extract at a low dose, 100 mg/kg. It is suggested that ethanolic extract of Ficus deltoidea at particular doses, possess fasting and postprandial antihyperglycemic activity as well as glucose tolerance activity in streptozotocin-induced diabetic rats. Penerbit UKM 2010 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/3661/1/Antihyperglycemic_and_Glucose_Tolerance_Activity.pdf Zainah Adam, and Muhajir Hamid, and Amin Ismail, and Shafii Khamis, and Norazizah Marsidi, (2010) Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats. Jurnal Sains Kesihatan Malaysia, 8 (1). pp. 25-30. ISSN 1675-8161 http://www.fsk.ukm.my/jurnal/jilid%208%281%29%202010/Bab%205.pdf |
| spellingShingle | Zainah Adam, Muhajir Hamid, Amin Ismail, Shafii Khamis, Norazizah Marsidi, Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats |
| title | Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats |
| title_full | Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats |
| title_fullStr | Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats |
| title_full_unstemmed | Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats |
| title_short | Antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats |
| title_sort | antihyperglycemic and glucose tolerance activity of ficus deltoidea ethanolic extract in diabetic rats |
| url | http://journalarticle.ukm.my/3661/1/Antihyperglycemic_and_Glucose_Tolerance_Activity.pdf http://journalarticle.ukm.my/3661/ http://www.fsk.ukm.my/jurnal/jilid%208%281%29%202010/Bab%205.pdf |
| url_provider | http://journalarticle.ukm.my/ |