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Chromenone-based GSK-3ß inhibitors as potential therapeutic targets for cardiovascular diseases: In silico study, molecular dynamics, and ADMET profiles

Glycogen synthase kinase-3 beta (GSK-3ß) regulates glycogen metabolism and many different cellulars, including apoptosis, signaling, and neural. It is a crucial therapeutic receptor in heart disease, type 2 diabetes, and Alzheimer’s. In this study, using computational methods, flavonoid compounds we...

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Main Authors: Min Zhang, San Zhou, Noor H. Obaid, Usama S. Altimari, Mohanad Adel Mohammed, Ahmed Kareem Obaid Aldulaim, Emad Salaam Abood, Hossam Kotb, Ayesheh Enayati, Vahid Khori, Hassan Mirzaei, Aref Salehi, Alireza Soltani, Mohd Sani Sarjadi, Md. Lutfor Rahman
格式: Article
语言:English
English
出版: Elsevier B.V. 2022
主题:
QD1-999 Chemistry
R5-920 Medicine (General)
在线阅读:https://eprints.ums.edu.my/id/eprint/35099/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/35099/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/35099/
https://www.sciencedirect.com/science/article/pii/S1878535222006049
https://doi.org/10.1016/j.arabjc.2022.104288
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https://eprints.ums.edu.my/id/eprint/35099/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/35099/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/35099/
https://www.sciencedirect.com/science/article/pii/S1878535222006049
https://doi.org/10.1016/j.arabjc.2022.104288

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