Novel injectable calcium phosphate bone cement from wet chemical precipitation method
Calcium phosphate cement has been prepared via chemical precipitation method for injectable bone filling materials. Calcium hydroxide, Ca(OH)2, and diammonium hydrogen phosphate, (NH4)2HPO4, were used as calcium and phosphorus precursors respectively. The synthesized powder was mixed with water a...
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| 主要な著者: | , , , , , |
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| フォーマット: | Conference or Workshop Item |
| 言語: | English English English |
| 出版事項: |
IOP Publishing Ltd.
2017
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| 主題: | |
| オンライン･アクセス: | http://irep.iium.edu.my/59498/7/59498_Novel%20Injectable%20Calcium%20Phosphate%20Bone%20_complete.pdf http://irep.iium.edu.my/59498/8/59498_Novel%20Injectable%20Calcium%20Phosphate%20Bone%20_scopus.pdf http://irep.iium.edu.my/59498/19/59498%20Novel%20injectable%20calcium%20phosphate%20WOS.pdf http://irep.iium.edu.my/59498/ http://iopscience.iop.org/article/10.1088/1757-899X/205/1/012012 |
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| 要約: | Calcium phosphate cement has been prepared via chemical precipitation method for
injectable bone filling materials. Calcium hydroxide, Ca(OH)2, and diammonium hydrogen
phosphate, (NH4)2HPO4, were used as calcium and phosphorus precursors respectively. The
synthesized powder was mixed with water at different powder-to-liquid (P/L) ratios, which was
adjusted at 0.8, 0.9, 1.0, 1.1 and 1.2. The influence of P/L ratio on the injectability, setting time
and mechanical strength of calcium phosphate cement paste has been evaluated. The
synthesized powder appeared as purely hydroxyapatite with nanosized and agglomerated
spherical particles. All cement pastes show excellent injectability except for the paste with P/L
ratio 1.2. Calcium phosphate cement with P/L ratio 1.1 shows the ideal cement for bone filler
application with good injectability, the initial and final setting times of 30 min and 160 min,
and the compression strength of 2.47 MPa. The result indicated that the newly developed
calcium phosphate cement is physically suitable for bone filler application. This paper presents
our investigation on the effect of P/L ratio on the handling and mechanical properties of
calcium phosphate cement prepared via wet chemical precipitation method. |
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