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Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration

Background: This study was done to explore the possibility of the usage of different viscosities in artificial tears (Systane Ultra and Hydration) in detecting changes in corneal aberration on dry eye patients. Methods: 103 diagnosed dry eyes were observed in this study and two different artificial...

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Main Authors: Halmi, Husna Alia, Hilmi, Mohd Radzi, Md Rejab, Noor Shazana, Wolffsohn, James Stuart
Format: Article
Language:English
Published: IIUM Press 2024
Subjects:
RE Ophthalmology
Online Access:http://irep.iium.edu.my/117399/13/117399_Impact%20of%20viscosity%20variations%20in%20dual-polymer%20artificial%20tears%20on%20corneal%20regularity%20and%20aberration.pdf
http://irep.iium.edu.my/117399/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/954/849
https://doi.org/10.31436/ijahs.v8i5
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spelling my.iium.irep.1173992025-01-06T04:26:31Z http://irep.iium.edu.my/117399/ Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration Halmi, Husna Alia Hilmi, Mohd Radzi Md Rejab, Noor Shazana Wolffsohn, James Stuart RE Ophthalmology Background: This study was done to explore the possibility of the usage of different viscosities in artificial tears (Systane Ultra and Hydration) in detecting changes in corneal aberration on dry eye patients. Methods: 103 diagnosed dry eyes were observed in this study and two different artificial tears with different viscosities were instilled randomly in each eye. Corneal aberration measurement with Fourier index (Spherical aberration (SA), trefoil and coma) was then captured for 10 minutes using CASIA with a 1-minute time interval. Normal saline was instilled before the treatment was given (referred to as baseline). Repeated measure analysis of variance (RM ANOVA) and paired sample t-test were used to evaluate the effects of artificial tears after instillation and comparison between each specific time interval respectively. The P-value of 0.05 was set as the level of significance. Results: Corneal aberration with artificial tears was then compared to normal saline and the results showed that there was no significant difference between artificial tears in terms of retention time after 10 minutes (p>0.05) in dry eye participants. Both groups demonstrated significant improvements from baseline and there was a significant difference from baseline (p<0.05). Conclusion: Instillation of high viscous artificial tear produce better uniformity of the corneal surface resulting in lower corneal aberration. IIUM Press 2024-12-27 Article PeerReviewed application/pdf en http://irep.iium.edu.my/117399/13/117399_Impact%20of%20viscosity%20variations%20in%20dual-polymer%20artificial%20tears%20on%20corneal%20regularity%20and%20aberration.pdf Halmi, Husna Alia and Hilmi, Mohd Radzi and Md Rejab, Noor Shazana and Wolffsohn, James Stuart (2024) Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration. International Journal of Allied Health Sciences, 8 (5). pp. 242-249. E-ISSN 2600-8491 https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/954/849 https://doi.org/10.31436/ijahs.v8i5
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic RE Ophthalmology
spellingShingle RE Ophthalmology
Halmi, Husna Alia
Hilmi, Mohd Radzi
Md Rejab, Noor Shazana
Wolffsohn, James Stuart
Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration
description Background: This study was done to explore the possibility of the usage of different viscosities in artificial tears (Systane Ultra and Hydration) in detecting changes in corneal aberration on dry eye patients. Methods: 103 diagnosed dry eyes were observed in this study and two different artificial tears with different viscosities were instilled randomly in each eye. Corneal aberration measurement with Fourier index (Spherical aberration (SA), trefoil and coma) was then captured for 10 minutes using CASIA with a 1-minute time interval. Normal saline was instilled before the treatment was given (referred to as baseline). Repeated measure analysis of variance (RM ANOVA) and paired sample t-test were used to evaluate the effects of artificial tears after instillation and comparison between each specific time interval respectively. The P-value of 0.05 was set as the level of significance. Results: Corneal aberration with artificial tears was then compared to normal saline and the results showed that there was no significant difference between artificial tears in terms of retention time after 10 minutes (p>0.05) in dry eye participants. Both groups demonstrated significant improvements from baseline and there was a significant difference from baseline (p<0.05). Conclusion: Instillation of high viscous artificial tear produce better uniformity of the corneal surface resulting in lower corneal aberration.
format Article
author Halmi, Husna Alia
Hilmi, Mohd Radzi
Md Rejab, Noor Shazana
Wolffsohn, James Stuart
author_facet Halmi, Husna Alia
Hilmi, Mohd Radzi
Md Rejab, Noor Shazana
Wolffsohn, James Stuart
author_sort Halmi, Husna Alia
title Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration
title_short Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration
title_full Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration
title_fullStr Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration
title_full_unstemmed Impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration
title_sort impact of viscosity variations in dual-polymer artificial tears on corneal regularity and aberration
publisher IIUM Press
publishDate 2024
url http://irep.iium.edu.my/117399/13/117399_Impact%20of%20viscosity%20variations%20in%20dual-polymer%20artificial%20tears%20on%20corneal%20regularity%20and%20aberration.pdf
http://irep.iium.edu.my/117399/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/954/849
https://doi.org/10.31436/ijahs.v8i5
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score 13.239859

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